Skip to main content
. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Toxicol In Vitro. 2022 Nov 6;86:105515. doi: 10.1016/j.tiv.2022.105515

Table 6A.

Predictivity of OptiSafe and Updated OptiSafe Compared to Eye Irritation Tests with OECD Guidelines for Detection of NC versus the Rest.

Test Method Sensitivity Specificity Accuracy Bal. Accuracy
STE1 88% 81% 85% 84.5%
BCOP (LLBO)2 94% 55% 83% 74.5%
EpiOcular3 96% 63% 80% 79.5%
ICE4 97% 76% 88% 86.5%
Ocular Irritection5 91% 59% 75% 75.0%
OptiSafe 100.0% 62.5% 86.8% 81.3%
Updated OptiSafe 100.0% 79.6% 92.8% 89.8%