Table 4. Associations between parish and clinical outcomes stratified by age.
Age strata | District | Parish | Intervals* | Interval risk of any symptomatic malaria | Interval risk of any microscopic parasitemia | Risk of symptomatic malaria if microscopic parasitemia present** | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n (%) | RR (95% CI) | p-value | n (%) | RR (95% CI) | p-value | % | RR (95% CI) | p-value | ||||
< 5 years | Busia | Buteba | 260 | 39 (15.0) | Reference | 63 (24.2) | Reference | 61.9 | Reference | |||
Tororo | Kayoro | 439 | 45 (10.3) | 0.68 (0.44–1.06) | 0.09 | 85 (19.4) | 0.81 (0.55–1.19) | 0.28 | 52.9 | 0.86 (0.56–1.31) | 0.48 | |
Osukuru | 247 | 59 (23.9) | 1.60 (1.05–2.42) | 0.03 | 81 (32.8) | 1.41 (0.94–2.12) | 0.10 | 72.8 | 1.18 (0.79–1.76) | 0.43 | ||
5–15 years | Busia | Buteba | 162 | 18 (11.1) | Reference | 70 (43.2) | Reference | 25.7 | Reference | |||
Tororo | Kayoro | 354 | 40 (11.3) | 1.01 (0.57–1.82) | 0.96 | 138 (39.0) | 0.90 (0.67–1.21) | 0.49 | 29.0 | 1.13 (0.64–2.00) | 0.68 | |
Osukuru | 204 | 41 (20.1) | 1.81 (1.01–3.27) | 0.047 | 92 (45.1) | 1.04 (0.76–1.43) | 0.79 | 44.6 | 1.74 (0.98–3.09) | 0.06 | ||
> 15 years | Busia | Buteba | 225 | 6 (2.7) | Reference | 41 (18.2) | Reference | 14.3 | Reference | |||
Tororo | Kayoro | 407 | 11 (2.7) | 1.07 (0.36–3.18) | 0.91 | 49 (12.0) | 0.64 (0.38–1.08) | 0.10 | 22.5 | 1.53 (0.57–4.15) | 0.40 | |
Osukuru | 228 | 14 (6.1) | 2.38 (0.80–7.08) | 0.12 | 32 (14.0) | 0.78 (0.43–1.39) | 0.39 | 43.8 | 2.99 (1.15–7.78) | 0.03 |
* approximately 28-day periods of observation between routine visits
** Number of intervals with any symptomatic malaria diagnosed / number of intervals with any microscopic parasitemia detected