Table 1.

Clinical details of recruited subjects in the study.

	Sample set 1			Sample set 2
Characteristics	HCs	MDD	p value	HCs	MDD	p value
Sample size (n)	360	354	–	67	143	–
Sex (male/female)	124/236	115/239	0.579a	29/38	65/78	0.129a
Age (years)
Range	23–69	18–70	–	19–66	18–66	–
Mean ± SEM	39.47 ± 0.5	40.08 ± 0.90	0.360b	37.21 ± 1.33	37.61 ± 1.14	0.762b
HDRS (mean ± SEM)		33.41 ± 0.49	–	3.36 ± 0.32	33.46 ± 0.76	8.17E−15c
Duration of illness (months)
Range	–	0.33–360		–	0.33–180
Mean ± SEM		50.91 ± 3.28		–	39.85 ± 3.60

Continuous variables are expressed as mean ± standard error of the mean (SEM).

HCs healthy controls, HDRS Hamilton Depression Rating Scale, MDD major depressive disorder.

^aAnalyzed by the Chi-square test.

^bAnalyzed by Mann–Whitney U test.

^cIndependent sample t-tests.