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. 2022 Dec 23;24:197–235. doi: 10.1016/j.bioactmat.2022.11.019

Table 7.

Summary of reviewed studies of cell-laden hydrogels for wound healing.

Biomaterials Cell line Cell density In vivo Main result Ref
GelMA-methacrylated hyaluronic acid (HAMA) Human Adipose derived stem cell (ADSCs) 0.5 × 106–2 × 106 cells/mL + Supported cell proliferation,
Enhanced vascularization		 [191]
Poly NIPAM- poly(amidoamine) Mice bone marrow mesenchymal stem cell (BMSC) 1 × 106 cells/mL + Secretion of TGF-β1 and bFGF by BMSCs.
Inhibition of inflammation, increase in wound contraction, angiogenesis, ECM secretion, and re-epithelialization in in vivo wound model for BMSC containing hydrogel.		 [192]
Chitosan-Gelatin Human Adipose derived stem cell (ADSCs) 1 × 106 cells/mL + Sustained release of ADSC, enhanced in vitro fibroblast migration, and increased capillary formation in vivo [196]