Fig. 6.

In vivo synergistic chemotherapy, PTT, and PDT of M_ICG-Pt on B16F10 tumor model. (a) Infrared thermal images of B16F10 tumor-bearing mice intratumorally injected with PBS, M_ICG or M_ICG-Pt and irradiated by 808-nm laser (0.6 W cm⁻²) for 5 min. (b–e) Tumor photographs (b), tumor volumes (c), tumor weights (d), and body weight (e) changes of mice after various treatments for 14 days. (−) indicated without NIR irradiation, and (+) indicated with NIR irradiation. Each experiment group has 3 mice (n = 3). Data are presented as the mean ± SD. n.s.: no significance, *p < 0.05, **p < 0.01, ***p < 0.001.