Table 2.
Demographics, socioeconomic status indicators, club drug use, and past postexposure prophylaxis (PEP) use and their bivariate associations with current and prior pre-exposure prophylaxis (PrEP) use compared with never used PrEP (N=63,015).
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Current PrEP use | Prior PrEP use | |||||||||
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Values (n=13,832) | RRRa (99.9% CI) | P value | Values (n=5118) | RRR (99.9% CI) | P value | |||||
| Categorical variables, n (%)b | |||||||||||
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Age (years) | ||||||||||
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13 to 24 | 1911 (13.82) | N/Ac | N/A | 959 (18.74) | N/A | N/A | |||
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25 to 34 | 5807 (41.98) | 2.75d (2.50-3.03) | <.001 | 2414 (47.17) | 2.28 (2.00-2.60) | <.001 | |||
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35 to 44 | 3273 (23.66) | 3.28 (2.95-3.65) | <.001 | 1044 (20.4) | 2.09 (1.79-2.44) | <.001 | |||
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≥45 | 2841 (20.54) | 2.59 (2.33-2.89) | <.001 | 701 (13.7) | 1.23 (1.08-1.51) | <.001 | |||
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Sexual orientation identity | ||||||||||
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Gay | 11,792 (85.25) | N/A | N/A | 4178 (81.63) | N/A | N/A | |||
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Bisexual | 1533 (11.08) | 0.30 (0.27-0.33) | <.001 | 711 (13.89) | 0.39 (0.34-0.44) | <.001 | |||
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Queer | 479 (3.46) | 1.11 (0.93-1.34) | .06 | 211 (4.12) | 1.39 (1.07-1.79) | <.001 | |||
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Straight | 28 (0.2) | 0.08 (0.04-0.16) | <.001 | 18 (0.35) | 0.15 (0.07-0.33) | <.001 | |||
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Gender | ||||||||||
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Cisgender man | 13,748 (99.39) | N/A | N/A | 5069 (99.04) | N/A | N/A | |||
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Transgender man | 84 (0.61) | 0.61 (0.41-0.91) | <.001 | 49 (0.96) | 0.97 (0.59-1.59) | .83 | |||
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Region | ||||||||||
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Northeast | 3294 (23.81) | N/A | N/A | 1562 (30.52) | N/A | N/A | |||
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Midwest | 2307 (16.68) | 0.71 (0.64-0.78) | <.001 | 1240 (24.23) | 0.68 (0.58-0.79) | <.001 | |||
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South | 4054 (29.31) | 0.66 (0.60-0.72) | <.001 | 833 (16.28) | 0.63 (0.55-0.72) | <.001 | |||
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West | 4131 (29.87) | 0.89 (0.81-0.97) | <.001 | 1466 (28.64) | 0.89 (0.78-1.02) | .004 | |||
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US possession | 35 (0.25) | 0.42 (0.23-0.77) | <.001 | 10 (0.2) | 0.32 (0.11-0.93) | <.001 | |||
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Military overseas | 6 (0.04) | 0.76 (0.16-3.50) | .55 | 3 (0.06) | 1.00 (0.13-7.71) | .99 | |||
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Unknown | 5 (0.04) | 0.36 (0.07-1.74) | .03 | 4 (0.08) | 0.76 (0.13-4.35) | .61 | |||
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Race and ethnicity | ||||||||||
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Black, non-Hispanic | 1311 (9.48) | 0.84 (0.75-0.94) | <.001 | 540 (8.1) | 1.07 (0.90-1.26) | .21 | |||
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Latino or Hispanic | 2359 (17.05) | 0.94 (0.86-1.03) | .02 | 1050 (9.5) | 1.29 (1.13-1.46) | <.001 | |||
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Multiracial | 1329 (9.61) | 0.21 (0.06-0.71) | <.001 | 630 (9.9) | 0.25 (0.05-1.33) | .006 | |||
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White, non-Hispanic | 7996 (57.81) | N/A | N/A | 2596 (7.4) | N/A | N/A | |||
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Another | 837 (6.05) | 0.94 (0.86-1.03) | .02 | 302 (7.8) | 1.24 (1.09-1.42) | <.001 | |||
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Health insurance status | ||||||||||
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Has private health insurance | 10,118 (73.15) | 2.79 (2.52-3.08) | <.001 | 2932 (7.5) | 0.96 (0.85-1.08) | .28 | |||
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Has public health insurance (eg, Medicaid) | 2293 (16.58) | 2.09 (1.85-2.36) | <.001 | 993 (8.9) | 1.08 (0.93-1.25) | .10 | |||
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Uninsured | 1421 (10.27) | N/A | N/A | 1193 (9.3) | N/A | N/A | |||
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Any club drug use (past 90 days)e | ||||||||||
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No | 10,512 (76) | N/A | N/A | 3719 (7.4) | N/A | N/A | |||
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Yes | 3320 (24) | 1.45 (1.34-1.57) | <.001 | 1399 (11.1) | 1.73 (1.55-1.93) | <.001 | |||
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Past PEP use | ||||||||||
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No | 10,564 (76.37) | N/A | N/A | 2281 (4.1) | N/A | N/A | |||
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Yes | 3268 (23.63) | 13.28 (11.73-15.04) | <.001 | 2837 (39.9) | 53.40 (46.42-61.43) | <.001 | |||
| Continuous variable, mean (SD) | |||||||||||
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Socioeconomic status ladder (range 1-10) | 7.47 (32.65) | 1.001 (1.000-1.003) | <.001 | 6.90 (31.02) | 1.001 (0.999-1.003) | .09 | ||||
aRRR: relative risk ratio.
bPercentages may not add up to 100 because of rounding.
cN/A: not applicable.
dItalicized relative risk ratio values are significant at P<.001.
eClub drugs include crack and cocaine; 3,4-methylenedioxy-methamphetamine (MMDA); gamma-hydroxybutyrate (GHB); ketamine; and methamphetamine.