TABLE 3.
All‐cause outpatient visits (n = 1730) | All‐cause hospitalizations (n = 125) | Phototherapy | Topical treatment | |||
---|---|---|---|---|---|---|
Frequency, [95% CI], (PPPM) | Duration between visits, Mean (SD), days | Frequency, [95% CI], (PPPM) | Duration, Mean (SD), days a | Frequency, [95% CI], (PPPM) | n (%) | |
Total | 2.0 [2.0, 2.0] | 14.5 (18.8) | 0.01 [0.01, 0.01] | 12.8 (18.8) | 0.18 [0.17, 0.19] | 1617 (93.5) |
TNF inhibitor | 1.7 [1.6, 1.9] | 17.0 (19.0) | 0.00 [0.00, 0.02] | 3 (0.0) | 0.00 [0.00, 0.02] | 22 (88) |
IL‐12/23 inhibitor | 1.4 [1.2, 1.5] | 21.7 (25.4) | 0.01 [0.00, 0.03] | 58.3 (49.5) | 0.00 [0.00, 0.00] | 21 (87.5) |
IL‐17 inhibitor | 2.3 [2.2, 2.4] | 12.3 (17.5) | 0.01 [0.00,0.01] | 6.0 (6.2) | 0.00 [0.00,0.01] | 44 (73.3) |
IL‐23 inhibitor | 1.7 [1.6, 1.9] | 17.0 (18.3) | 0.00 [0.00, 0.02] | 2 (0.0) | 0.00 [0.00, 0.00] | 20 (71.4) |
PDE‐4 inhibitor | 2.1 [2.0, 2.1] | 14.0 (17.6) | 0.01 [0.00, 0.01] | 9.2 (19.0) | 0.25 [0.24, 0.26] | 917 (96.2) |
Immunosuppressant | 1.8 [1.8, 1.8] | 15.7 (21.1) | 0.01 [0.01, 0.02] | 14.1 (15.1) | 0.04 [0.04, 0.05] | 336 (89.1) |
Vitamin A | 2.0 [2.0, 2.1] | 14.2 (19.8) | 0.01 [0.01, 0.02] | 15.4 (16.1) | 0.22 [0.21, 0.24] | 257 (97.7) |
Note: TNF inhibitor includes adalimumab. IL‐12/23 inhibitor includes ustekinumab. IL‐23 inhibitor includes guselkumab. IL‐17 inhibitors include secukinumab and brodalumab. PDE‐4 inhibitor includes apremilast. Immunosuppressant includes cyclosporin. Vitamin A includes etretinate.
Abbreviations: CI, confidence interval; IL, interleukin; n, number of patients; PDE‐4, phosphodiesterase‐4; PPPM, per person per month; SD, standard deviation; TNF, tumor necrosis factor.
For patients having at least one hospitalization.