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. 2022 Aug 10;49(11):1106–1117. doi: 10.1111/1346-8138.16543

TABLE 3.

Healthcare resource utilization during the 12‐month follow‐up period

All‐cause outpatient visits (n = 1730) All‐cause hospitalizations (n = 125) Phototherapy Topical treatment
Frequency, [95% CI], (PPPM) Duration between visits, Mean (SD), days Frequency, [95% CI], (PPPM) Duration, Mean (SD), days a Frequency, [95% CI], (PPPM) n (%)
Total 2.0 [2.0, 2.0] 14.5 (18.8) 0.01 [0.01, 0.01] 12.8 (18.8) 0.18 [0.17, 0.19] 1617 (93.5)
TNF inhibitor 1.7 [1.6, 1.9] 17.0 (19.0) 0.00 [0.00, 0.02] 3 (0.0) 0.00 [0.00, 0.02] 22 (88)
IL‐12/23 inhibitor 1.4 [1.2, 1.5] 21.7 (25.4) 0.01 [0.00, 0.03] 58.3 (49.5) 0.00 [0.00, 0.00] 21 (87.5)
IL‐17 inhibitor 2.3 [2.2, 2.4] 12.3 (17.5) 0.01 [0.00,0.01] 6.0 (6.2) 0.00 [0.00,0.01] 44 (73.3)
IL‐23 inhibitor 1.7 [1.6, 1.9] 17.0 (18.3) 0.00 [0.00, 0.02] 2 (0.0) 0.00 [0.00, 0.00] 20 (71.4)
PDE‐4 inhibitor 2.1 [2.0, 2.1] 14.0 (17.6) 0.01 [0.00, 0.01] 9.2 (19.0) 0.25 [0.24, 0.26] 917 (96.2)
Immunosuppressant 1.8 [1.8, 1.8] 15.7 (21.1) 0.01 [0.01, 0.02] 14.1 (15.1) 0.04 [0.04, 0.05] 336 (89.1)
Vitamin A 2.0 [2.0, 2.1] 14.2 (19.8) 0.01 [0.01, 0.02] 15.4 (16.1) 0.22 [0.21, 0.24] 257 (97.7)

Note: TNF inhibitor includes adalimumab. IL‐12/23 inhibitor includes ustekinumab. IL‐23 inhibitor includes guselkumab. IL‐17 inhibitors include secukinumab and brodalumab. PDE‐4 inhibitor includes apremilast. Immunosuppressant includes cyclosporin. Vitamin A includes etretinate.

Abbreviations: CI, confidence interval; IL, interleukin; n, number of patients; PDE‐4, phosphodiesterase‐4; PPPM, per person per month; SD, standard deviation; TNF, tumor necrosis factor.

a

For patients having at least one hospitalization.