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. 2022 Aug 2;179(21):4941–4957. doi: 10.1111/bph.15893

FIGURE 3.

FIGURE 3

Lifetime analysis of statin induced ryanodine RyR1 activity. (a) The effect of cytosolic atorvastatin on RyR1 mean open and closed times. Mean ± SEM; n = 5, *p < .05. (b) Open and closed life‐time distributions and probability density functions for a representative RyR1 channel in control conditions (10‐μM Ca2+, top) and after addition of 10‐μM atorvastatin (Ator)(bottom). The time constants (τ) and percentage areas are shown