Table 1.
Correlation between E2F7 transcript and clinicopathological features in 87 HCC specimens
| Clinicopathologic parameters | FOXC1 expression | p * | |
|---|---|---|---|
| Low (n = 24) | High (n = 63) | ||
| Age (years) | |||
| ≤50 | 14 | 32 | 0.633 |
| >50 | 10 | 31 | |
| Gender | |||
| Male | 16 | 32 | 0.231 |
| Female | 8 | 31 | |
| Diameter (cm) | |||
| ≤5 | 18 | 25 | 0.023 |
| >5 | 9 | 38 | |
| TNM stage | |||
| I–II | 15 | 17 | 0.016 |
| III–IV | 12 | 46 | |
| Tumor encapsulation | |||
| Absent | 10 | 26 | 0.815 |
| Present | 17 | 37 | |
| Tumor microsatellite formation | |||
| Absent | 16 | 21 | 0.035 |
| Present | 11 | 42 | |
| Venous invasion | |||
| No | 14 | 18 | 0.054 |
| Yes | 13 | 45 | |
| HBsAg | |||
| Negative | 5 | 6 | 0.295 |
| Positive | 22 | 57 | |
| AFP (ng/ml) | |||
| ≤400 | 17 | 3 | <0.001 |
| >400 | 10 | 60 | |
| Cirrhosis | |||
| Absent | 5 | 5 | 0.159 |
| Present | 22 | 58 | |
Note: E2F7 level associated with clinicopathologic features in 87 HCC patients, including age, gender, tumor size, tumor stage (AJCC), tumor encapsulation, tumor microsatellite formation, vein invasion, HBsAg status, AFP level, and liver cirrhosis. Statistical significance was assessed by Fisher's exact text.
Abbreviation: AFP, alpha‐fetoprotein; HCC, hepatocellular carcinoma.
*
p < 0.05.