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. 2022 Aug 30;151(12):2161–2171. doi: 10.1002/ijc.34257

FIGURE 2.

FIGURE 2

ROS1 fusion structure in CRC. (A) Schematic representation of ROS1 breakpoints located in introns 30 to 34, and exons 31 and 35 of the extracellular and transmembrane ROS1 domain. (B) Schematic of predicted intron‐exon structure of identified ROS1 fusions GOPC‐ROS1, DCBLD1‐ROS1 and MCM9‐ROS1 fusions occur caused by microdeletions within the chromosomal region 6q21