TABLE 2.
Characteristics of the Patients according to the Perfusion Pattern at 48 Hours
| Characteristic | Normal Perfusion, n = 21 | Abnormal Perfusion, n = 15 | p |
|---|---|---|---|
| Demographics | |||
| Age, years, median (IQR) | 71 (57–77) | 76 (71–86) | 0.05 |
| Women, n (%) | 10 (48%) | 8 (53%) | 0.73 |
| Atrial fibrillation, n (%) | 1 (5%) | 2 (13%) | 0.35 |
| Diabetes mellitus, n (%) | 3 (14%) | 4 (27%) | 0.35 |
| Hypertension, n (%) | 14 (67%) | 12 (80%) | 0.37 |
| Hospital admission | |||
| SBP, mmHg, median (IQR) | 138 (131–157) | 145 (120–155) | 0.98 |
| DBP, mmHg, median (IQR) | 73 (71–81) | 71 (65–80) | 0.43 |
| Glucose, mg/dl, median (IQR) | 115 (98–134) | 140 (118–166) | 0.01 |
| NIHSS, median (IQR) | 9 (7–19) | 15 (11–20) | 0.55 |
| IV alteplase before EVT, n (%) | 7 (33%) | 7 (47%) | 0.41 |
| Time to randomization, min, median (IQR) | 315 (204–518) | 393 (297–450) | 0.46 |
| CTP admission | |||
| Hypoperfusion, ml, median (IQR) | 50.5 (34.1–83.8) | 55.7 (27.2–93.5) | 0.71 |
| Core median, ml (IQR) | 10.0 (7.1–14.7) | 6.2 (2.5–12.5) | 0.59 |
| Mismatch, % (95% CI) | 86 (72–96) | 88 (81–94) | 0.73 |
| Final eTICI score | |||
| eTICI score | 0.13 | ||
| eTICI 2b50 | 0 (0%) | 2 (100%) | |
| eTICI 2b67 | 6 (46%) | 7 (54%) | |
| eTICI 2c | 5 (63%) | 3 (38%) | |
| eTICI 3 | 10 (77%) | 3 (23%) | |
| Infarct course at 48 hours | |||
| Infarct expansion ratio, median (IQR) | 0.7 (0.5–2.1) | 3.2 (1.8–4.3) | 0.06 |
| Infarct volume, ml, median (IQR) | 5.7 (4.9–12.2) | 18.6 (7.7–32.1) | 0.02 |
CI = confidence interval; CTP = computed tomography perfusion; DBP = diastolic blood pressure; eTICI: expanded Thrombolysis in Cerebral Infarction scale; EVT = endovascular treatment; IQR = interquartile range; IV = intravenous; NIHSS = National Institutes of Health Stroke Scale; SBP = systolic blood pressure.