Table 1.
Tissue tropism and pathogenicity of the Australian IBV strains studied to date
| Isolate | Genotype | Tissue tropism | Pathogenicity | Mortality rate | Clinical signs | Gross lesions | Histopathological lesions | Reference |
|---|---|---|---|---|---|---|---|---|
| N1/62 | GI‐5 | K | High | 80–90% | Prominent nephritis | Urate deposits in kidneys | Severe in kidneys | Ignjatovic et al 151 |
| K‐RT | High | 90% | Not determined | Not determined | Severe in kidneys, mild in trachea | Sapats et al, 1996 | ||
| Q1/65 | ND | K | High | 80–90% | Prominent nephritis | Urate deposits in kidneys | Severe in kidneys | Ignjatovic et al 151 |
| N8/74 | ND | K | High | 80–90% | Prominent nephritis | Urate deposits in kidneys | Severe in kidneys | Ignjatovic et al 151 |
| Q1/61 | ND | K | Moderate | 30–65% | Moderate nephritis | Irregular or no urate deposits | Mild to severe in kidneys | Ignjatovic et al 151 |
| Q1/63 | ND | K | Moderate | 30–65% | Moderate nephritis | Irregular or no urate deposits | Mild to severe in kidneys | Ignjatovic et al 151 |
| Q1/73 | GI‐6 | K | Moderate | 30–65% | Moderate nephritis | Irregular or no urate deposits | Mild to severe in kidneys | Ignjatovic et al 151 |
| N1/75 | ND | K | Moderate | 30–65% | Moderate nephritis | Irregular or no urate deposits | Mild to severe in kidneys | Ignjatovic et al 151 |
| Q1/76 | GI‐6 | K | Moderate | 30–65% | Moderate nephritis | Irregular or no urate deposits | Mild to severe in kidneys | Ignjatovic et al 151 |
| NT2/89 | ND | K | Moderate | 30–65% | Moderate nephritis | Irregular or no urate deposits | Mild to severe in kidneys | Ignjatovic et al 151 |
| V2/71 | GI‐6 | K | Low | 5–15% | Mild to mod. nephritis | No gross lesions in kidneys | Mild to severe in kidneys | Ignjatovic et al 151 |
| N4/81 | ND | K | Low | 5–15% | Mild to mod. nephritis | No gross lesions in kidneys | Mild to severe in kidneys | Ignjatovic et al 151 |
| N25/87 | ND | K | Low | 5–15% | Mild to mod. nephritis | No gross lesions in kidneys | Mild to severe in kidneys | Ignjatovic et al 151 |
| Vaccine 5 | ND | K | Low | 5–15% | Mild to mod. nephritis | No gross lesions in kidneys | Mild to severe in kidneys | Ignjatovic et al 151 |
| N2/62 | ND | U | Low | No mortality | Mild to trans. nephritis | No gross lesions in kidneys | Mild in kidneys | Ignjatovic et al 151 |
| Q1/64 | ND | U | Low | No mortality | Mild to trans. nephritis | No gross lesions in kidneys | Mild in kidneys | Ignjatovic et al 151 |
| N1/81 | ND | U | Low | No mortality | Mild to trans. nephritis | No gross lesions in kidneys | Mild in kidneys | Ignjatovic et al 151 |
| Vaccine 1 | ND | U | Low | No mortality | Mild to trans. nephritis | No gross lesions in kidneys | Mild in kidneys | Ignjatovic et al 151 |
| V1/71 | GI‐5 | RT (t) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | No lesions detected | Ignjatovic et al 151 |
| V4/90 | ND | RT (t) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | No lesions detected | Ignjatovic et al 151 |
| V6/92 | GIII‐1 | RT (t) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | No lesions detected | Ignjatovic et al 151 |
| N6/88 | ND | RT (at) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | Mild in kidneys | Ignjatovic et al 151 |
| Q1/89 | ND | RT (at) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | No lesions detected | Ignjatovic et al 151 |
| N3/89 | ND | RT (at) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | No lesions detected | Ignjatovic et al 151 |
| V19/91 | ND | RT (at) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | No lesions detected | Ignjatovic et al 151 |
| V2/93 | ND | RT (at) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | Mild in kidneys | Ignjatovic et al 151 |
| V3/93 | ND | RT (at) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | No lesions detected | Ignjatovic et al 151 |
| N1/94 | ND | RT (at) | Low | No mortality | No signs of nephritis | No gross lesions in kidneys | No lesions detected | Ignjatovic et al 151 |
| VicS | GI‐6 | K‐RT | Low | No mortality | ND | ND | Mild in kidneys and trachea | Sapats et al, 1996 |
| N3/62 | GI‐5 | K‐RT | Low | No mortality | ND | ND | Mild in trachea | Sapats et al, 1996 |
| N9/74 | GI‐5 | K‐RT | High | 96% | ND | ND | Mild in kidneys and trachea | Sapats et al, 1996 |
| N2/75 | GI‐6 | K‐RT | Moderate | 32% | ND | ND | Moderate in kidneys and trachea | Sapats et al, 1996 |
| N1/88 | GIII‐1 | RT | Low | No mortality | ND | ND | Moderate in trachea | Sapats et al, 1996 |
| Q3/88 | GIII‐1 | RT | Low | No mortality | ND | ND | Moderate in trachea | Sapats et al, 1996 |
| V5/90 | GI‐6 | K‐RT | Low | No mortality | ND | ND | Moderate in trachea | Sapats et al, 1996 |
| V18/91 | GIII‐1 | RT | Low | No mortality | ND | ND | Mild in trachea | Sapats et al, 1996 |
| N1/08 | GIII‐1 | RT | Low | No mortality | Mild respiratory signs | ND | Lesions in the mucosa of trachea | Hewson et al 171 |
Abbreviations: at, atypical; K, kidney; mod, moderate; ND, not determined; RT, respiratory tract; t, typical; trans, transient; U, uncertain/mixed.