TABLE 2.
Clinical data of wire myography and placental explant experiments
| Wire myography | Explants | |||
|---|---|---|---|---|
| Healthy (n= 47) | Pre‐eclampsia (n = 20) | Healthy (n = 7) | Pre‐eclampsia (n = 7) | |
| Maternal age (years) | 33 (30–35) | 31 (29–34) | 33 (27–38) | 31 (29–40) |
| Parity | * | |||
| 0 | 14 (29.8%) | 3 (15.0%) | 2 (28.6%) | 5 (71.4%) |
| 1 | 10 (21.3%) | 12 (60.0%) | 5 (71.4%) | 1 (14.3%) |
| >1 | 23 (48.9%) | 5 (25.0%) | 0 (0.0%) | 1 (14.3%) |
| Ethnicity | ||||
| Caucasian | 31 (67.4%) | 15 (83.3%) | 4 (57.1%) | 5 (71.4%) |
| Other | 15 (32.6%) | 3 (16.7%) | 3 (42.9%) | 2 (28.6%) |
| Missing (n) | 1 | 2 | 0 | 0 |
| Body mass index (kg·m−2) | 23.2 (21.1–28.8) | 26.8 (24.8–31.2) | 23.6 (19.4–30.1) | 30.1 (24.8–35) * |
| Missing (n) | 1 | 4 | 0 | 0 |
| Highest diastolic blood pressure (mmHg) | 77 (71–80) | 108 (100–111) * | 83 (75–90) | 109 (98–135) * |
| Highest systolic blood pressure (mmHg) | 125 (120–136) | 160 (155–173) * | 129 (121–138) | 186 (140–220) * |
| Highest mean arterial pressure (mmHg) | 93 (88–99) | 124 (120–136) * | 98 (90–106) | 136 (113–163) * |
| Urinary protein/creatinine ratio (mmol·mg−1) | NM | 164 (39–482) | NM | 68 (29–813) |
| Missing (n) | 1 | 0 | ||
| Mode of delivery | ||||
| Primary caesarean section | 47 (100.0%) | 19 (95.0%) | 6 (85.7%) | 5 (71.4%) |
| Secondary caesarean section | 0 (0.0%) | 1 (5.0%) | 0 (0.0%) | 0 (0.0%) |
| Vaginally | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 2 (14.3%) |
| Gestational age (weeks+days) | 39+0 (39+0–39+1) | 30+2 (28+1–31+4) * | 39+0 (38+4–39+2) | 31+0 (28+3–34+0) * |
| Sex | ||||
| Female | 19 (40.4%) | 12 (60.0%) | 4 (57.1%) | 3 (42.9%) |
| Male | 28 (59.6%) | 8 (40.0%) | 3 (42.9%) | 4 (57.1%) |
| Foetal birth weight (g) | 3470 (3335–3720) | 1128 (1011–1441) * | 3320 (2590–3820) | 1125 (485–3175) * |
| Foetal birth centile | * | |||
| <3rd | 0 (0.0%) | 10 (50.0%) | 0 (0.0%) | 3 (42.9%) |
| 3rd–10th | 3 (6.4%) | 6 (30.0%) | 2 (28.6%) | 1 (14.3%) |
| ≥10th | 44 (93.6%) | 4 (20.0%) | 5 (71.4%) | 3 (42.9%) |
| Placental weight (g) | 654 (561–734) | 276 (247–354) * | 510 (444–565) | 268 (152–478) * |
| Missing (n) | 9 | 1 | 1 | 1 |
Note: Numerical variables are shown as median and statistically tested by Kruskal–Wallis test. Categorical variables are shown as number of cases (%) and statistically tested by chi‐square test.
Abbreviation: NM, not measured.
*
P < 0.05 versus healthy.