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. 2022 Aug 3;52(11):1276–1290. doi: 10.1111/cea.14198

TABLE 2.

Investigations and diagnostics

Secondary Services (N = 126) Tertiary Services (N = 28) All services
% (n/N) % (n/N) % (n/N)
Investigations
Specific IgE 100 (126/126) 100 (28/28) 100 (154/154)
Skin prick testing 95 (120/126) 100 (28/28) 96 (148/154)
Component resolved diagnostic testing b 71 (89/126) 89 (25/28) 74 (114/154)
ISAC macro‐array testing 21 (27/126) 46 (13/28) 26 (40/154)
Intradermal testing 5 (6/126) 68 (19/28) 16 (25/154)
Patch testing 2 (3/126) 7 (2/28) 3 (5/154)
Spirometry a 59 (74/126) 79 (22/28) 62 (96/154)
Exhaled nitric oxide b 25 (32/126) 54 (15/28) 31 (47/154)
Other c 1 (1/126) 11 (3/28) 3 (4/154)
Skin prick testing
Skin prick testing available on same day a 93 (111/120) 96 (27/28) 93 (138/148)
Skin testing for drugs, food, venom and latex b 9 (11/120) 46 (13/28) 16 (24/148)
Staff undertaking skin prick testing
Consultant 31 (37/120) 14 (4/28) 28 (41/148)
Associate specialist 3 (3/120) 4 (1/28) 3 (4/148)
Nurse 91 (109/120) 100 (28/28) 93 (137/148)
Specialist registrar 2 (2/120) 4 (1/28) 2 (3/148)
Laboratory technician 1 (1/120) 0 (0/28) 1 (1/148)
Dietician 4 (5/120) 14 (4/28) 6 (9/148)
Other d 7 (8/120) 0 (0/28) 5 (8/148)
Skin prick testing undertaken
Foods—commercial SPT solutions 99 (119/120) 100 (28/28) 99 (147/148)
Foods—fresh whole foods 93 (111/120) 100 (28/28) 94 (139/148)
Aeroallergens 93 (112/120) 96 (247/28) 94 (139/148)
Latex 71 (85/120) 86 (24/28) 74 (109/148)
Bee/wasp venom 26 (31/120) 54 (15/28) 31 (46/148)
Drugs 18 (22/120) 68 (19/28) 28 (41/148)
Other e 0 (0/120) 4 (1/28) 1 (1/148)
Skin prick testing to whole foods
Tahini (sesame) 54 (59/110) 64 (18/28) 56 (77/138)
Fresh cow's milk 62 (68/110) 61 (17/28) 62 (85/138)
Raw egg white 30 (33/110) 32 (9/28) 30 (42/138)
Family brought food 93 (102/110) 96 (27/28) 93 (129/138)
Nuts 38 (42/110) 50 (14/28) 41 (56/138)
Component testing
Peanut 98 (86/88) 96 (23/24) 97 (109/112)
Hazelnut 74 (65/88) 83 (20/24) 76 (85/112)
Venom 17 (15/88) 75 (18/24) 29 (33/112)
Birch 42 (37/88) 88 (21/24) 52 (58/112)
Other 33 (29/88) 63 (15/24) 39 (44/112)
Peanut specific components (if peanut component testing undertaken)
ara h1 56 (48/85) 48 (11/23) 55 (59/108)
ara h2 98 (83/85) 100 (23/23) 98 (106/108)
ara h3 40 (34/85) 39 (9/23) 40 (43/108)
ara h8 87 (74/85) 78 (18/23) 85 (92/108)
ara h9 51 (43/85) 48 (11/23) 50 (54/108)
Hazelnut specific components (if hazelnut component testing undertaken)
cor a1 73 (45/62) 90 (18/20) 77 (63/82)
cor a8 77 (48/62) 80 (16/20) 78 (64/82)
cor a9 84 (52/62) 75 (15/20) 82 (67/82)
cor a14 84 (52/62) 80 (16/20) 83 (68/82)
Food & Drug challenges
Provides food challenges b 90 (114/126) 100 (28/28) 92 (142/154)
Provides drug challenges b 44 (56/126) 96 (27/28) 54 (83/154)
Staff undertaking drug challenges
Consultant 45 (25/56) 59 (16/27) 49 (41/83)
Associate specialist 7 (4/56) 4 (1/27) 6 (5/83)
Specialist registrar 7 (4/56) 26 (7/27) 13 (11/83)
Allergy nurse specialist 50 (28/56) 78 (21/27) 59 (49/83)
Paediatric nurse 43 (24/56) 33 (9/27) 40 (33/83)
Dietician 0 (0/56) 0 (0/27) 0 (0/83)
Other f 9 (5/56) 0 (0/27) 6 (5/83)
Drug challenges undertaken
Analgesics—paracetamol 55 (31/56) 85 (23/27) 65 (54/83)
Analgesics—NSAIDs 55 (31/56) 81 (22/27) 64 (53/83)
Antibiotics—IV 5 (3/56) 56 (15/27) 22 (18/83)
Antibiotics—oral 98 (55/56) 100 (27/27) 99 (82/83)
Local anaesthetics 11 (6/56) 70 (19/27) 30 (25/83)
General anaesthetics b 2 (1/56) 44 (12/27) 16 (13/83)
Other g 4 (2/56) 19 (5/27) 8 (7/83)
Open food challenge location
Paediatric day ward 80 (90/113) 71 (20/28) 78 (110/141)
Dedicated challenge unit 1 (1/113) 21 (6/28) 5 (7/141)
Outpatient department 8 (9/113) 11 (3/28) 9 (12/141)
Inpatient ward 20 (23/113) 4 (1/28) 17 (24/141)
Supervised feeds location
Paediatric day ward 73 (30/41) 53 (9/17) 67 (39/58)
Dedicated challenge unit 0 (0/41) 29 (5/17) 9 (5/58)
Outpatient department 20 (8/41) 41 (7/17) 26 (15/58)
Inpatient ward 17 (7/41) 12 (2/17) 16 (9/58)
Staff undertaking food challenges
Consultant 25 (28/114) 39 (11/28) 27 (39/142)
Associate specialist 5 (6/114) 7 (2/28) 6 (8/142)
Specialist registrar 4 (5/114) 18 (5/28) 7 (10/142)
Allergy nurse specialist 39 (45/114) 64 (18/28) 44 (63/142)
Paediatric nurse 69 (79/114) 57 (16/28) 67 (95/142)
Dietician 3 (3/114) 4 (1/28) 3 (4/142)
Other h 7 (8/114) 4 (1/28) 6 (9/142)
Challenge service configuration
Resuscitation facilities available for challenge a 98 (112/114) 100 (28/28) 99 (140/142)
≥2 challenges performed per month a 99 (110/111) 100 (28/28) 99 (138/139)
Supervision of ≤2 challenges per nurse a 89 (93/105) 82 (23/28) 87 (116/133)
Written information provided for challenges a 86 (98/114) 93 (26/28) 87 (124/142)
Parental consent obtained for challenges a 69 (78/113) 82 (23/28) 72 (101/141)
Challenge database kept a 64 (73/114) 86 (24/28) 68 (97/142)
a

Secondary Care BSACI Standard.

b

Specialist Paediatric Allergy Service Standards.

c

Other: Tertiary—basophil activation tests (BAT tests) (n = 1), ocular testing including visual acuity, intraocular pressure, staining and anterior rhinoscopy (n = 1), exercise challenge test (n = 2). Secondary—patch testing of standard dermatology panel (n = 1).

d

Other: includes healthcare assistants and ENT staff.

e

Other: includes major and minor determinants.

f

Other: includes junior doctor (with support) and clinical support worker.

g

Other: steroids, immunosuppressants, biologicals, codeine and “all” drugs.

h

Other: includes nurse practitioner, nurse clinician, associate practitioner, healthcare assistant and Senior House Officer.