TABLE 1.

Concordance between MRD results by RT‐qPCR and MFC

MFC MRD	RT‐qPCR MRD in bone marrow		RT‐qPCR MRD in peripheral blood
	Positive (≥0.1%)	Negative (<0.1%)	Positive (≥0.1%)	Negative (<0.1%)
All time points
Positive (≥0.1%)	3	1	2	0
Negative (<0.1%)	9	9	6	11
Concordance	54%		68%
K‐value	0.141 (p = 0.364)		0.278 (p = 0.080)
No. samples	22		19
Day 15
Positive (≥0.1%)	3	0	2	0
Negative (<0.1%)	6	1	5	2
Concordance	40%		44%
K‐value	0.091 (p = 0.490)		0.151 (p = 0.391)
No. samples	10		9
BC
Positive (≥0.1%)	0	1	0	0
Negative (<0.1%)	3	8	1	9
Concordance	67%		90%
K‐value	−0.143 (p = 0.546)
No. samples	12		10

Abbreviations: MFC, multiparameter flow cytometry; MRD, measurable residual disease; RT‐qPCR, real‐time quantitative polymerase chain reaction.