TABLE 3.
EPF versus EBV‐CTRL group—% changes post ELVR
| N = 14 both groups | CV negative EBV‐CTRL—difference at 6 months | CV positive EPF group—difference at 6 months | p value |
|---|---|---|---|
| Post‐BD FEV1 (% change) | 27.7 (5.3) | 19.7 (6.3) | <0.05 |
| Post‐BD FVC (% change) | 15.9 (5.6) | 14.7 (5.2) | NS |
| TLC (% change) | −5.8 (1.5) | −4.0 (1.8) | NS |
| RV (% change) | −20.1 (5.6) | −16.2 (4.7) | NS |
| DLCO (% predicted) | 6.5 (5.0) | 6.1 (3.4) | NS |
| KCO (% change) | 9.4 (3.8) | 7.0 (3.6) | NS |
| 6MWD (% change) | 28.4 (11.0) | 25.8 (4.9) a | NS |
| SGRQ (% change) | −28.8 (4.7) | −22.8 (5.6) | NS |
| LUL volume (% change) | −46.1 (6.0) | −43.4 (7.2) | NS |
Note: Data are presented as n (%) or mean ± SEM, unless otherwise stated.
Abbreviations: BD, bronchodilator; CV, collateral ventilation; DLCO, diffusing capacity for carbon monoxide; EBV‐CTRL, endobronchial valve control group; ELVR, endoscopic lung volume reduction; EPF, endobronchial polymer foam; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; LUL, left upper lobe; RV, residual volume; TLC, total lung capacity.
a
n = 12—as two subjects from rural areas were unable to travel to have 6MWD performed in an appropriate timeframe.