Table 2.
Major differentially methylated positions (DMPs, Δmeth > 5%)
| DMP | Chr | BP | Gene | Feature | CGI | Δmeth | FDR | mQTLs (GRCh37) |
|---|---|---|---|---|---|---|---|---|
| cg10070864 | 15 | 57664490 | IGR | Shelf | 0.090 | 0.002 |
15:57665782 15:57667027 |
|
| cg07199764 | 1 | 5347468 | IGR | Opensea | − 0.113 | 0.004 |
1:5343656 1:5346474 1:5346800 1:5347155 1:5347457 1:5348270 1:5348478 1:5350257 |
|
| cg19192981 | 15 | 57664704 | IGR | Shelf | 0.085 | 0.004 |
15:57665782 15:57667027 |
|
| cg07499182 | 13 | 33825496 | STARD13 | Body | Opensea | − 0.064 | 0.005 |
13:33824770 13:33824988 13.33826125 13.33829245 13:33829571 |
| cg25304129 | 22 | 26125490 | IGR | Opensea | 0.050 | 0.010 | – | |
| cg17015133 | 1 | 155111332 | RAG1AP1 | 3'UTR | Shore | − 0.052 | 0.011 | 1:155106697 |
| cg14433904 | 8 | 78518428 | IGR | Opensea | 0.056 | 0.015 |
8:78519059 8.78519337 |
|
| cg24833027 | 8 | 1897969 | ARHGEF10 | Body | Shelf | 0.067 | 0.019 |
8:1902750 8:1899691 8:1902112 8:1897657 8:1900410 8:1900911 8:1900546 8.1901176 8.1899381 8:1895934 |
| cg00401101 | 5 | 16509323 | FAM134B | TSS1500 | Opensea | 0.060 | 0.021 |
5:16508674 5:16512364 5:16514269 |
| cg08434374 | 11 | 44467306 | IGR | Opensea | 0.057 | 0.022 |
11:44469734 11:44471561 |
|
| cg03453431 | 7 | 157225567 | IGR | Opensea | − 0.054 | 0.023 | 7:157226016 | |
| cg16958467 | 15 | 57655799 | IGR | Opensea | 0.108 | 0.024 |
15:57655776 15:57656919 |
|
| cg00541777 | 2 | 3652840 | COLEC11 | TSS1500 | Opensea | 0.073 | 0.033 |
2:3650466 2:3652616 2:3654290 2:3654683 |
| cg01156747 | 7 | 120659 | IGR | Island | − 0.142 | 0.035 |
7:120429 7:120174 7:124276 7:124586 7:116077 7:116054 7:116969 7:122450 7:121755 7:117441 |
|
| cg17322118 | 1 | 85743732 | BCL10 | TSS200 | Shore | 0.053 | 0.035 |
1:85744472 1:85740024 1:85742860 1:85738953 |
| cg12257246 | 8 | 25240570 | DOCK5 | Body | Opensea | − 0.050 | 0.038 |
8:25240100 8:25245432 |
| cg00267320 | 10 | 111533258 | IGR | Opensea | 0.058 | 0.040 |
10:111528480 10:111537595 |
|
| cg00570954 | 12 | 94281309 | IGR | Opensea | 0.056 | 0.042 |
12:94281245 12:94285952 12:94282740 |
|
| cg13883027 | 2 | 62892060 | IGR | Opensea | 0.145 | 0.043 |
2:62887884 2:62890171 2:62892323 |
|
| cg25261547 | 19 | 49363369 | PLEKHA4 | Body | Opensea | − 0.052 | 0.046 | 19:49364511 |
| cg21728101 | 7 | 1979360 | MAD1L1 | Body | Shore | − 0.052 | 0.048 |
7:1976457 7.1983928 |
| cg14859874 | 1 | 154238265 | UBAP2L | Body | Opensea | − 0.122 | 0.049 |
1:154238063 1:154239283 1:154243115 1:154243245 |
Δmeth delta methylation beta value; FDR false discovery rate; CHR chromosome; BP base position, CGI CpG island, mQTL methylation quantitative trait loci, IGR intergenic region, TSS200 transcription start site 200, TSS1500 transcription start site 1500, 3′UTR 3′ untranslated region