Fig. 7.

Effect of paclitaxel (PTX) on TIMP-2 knocked down CRISPR/Cas9 and siRNA transfected cells and their controls. A, B The cell lines/cells are described in the legend for Fig. 3. Cell lines were treated for 48 h with varying concentrations of PTX, and the IC₅₀ values (the concentration that kills 50% of the cells) were determined by MTT assay. Graphs are representative of three independent experiments done in triplicate