TABLE 4.
Significance of protection obtained through vaccination
Vaccine | No. of animals:
|
P value fora:
|
|||||
---|---|---|---|---|---|---|---|
Self-curing | Treated for:
|
Days to treatment | Parasitemia at treatment | Days to peak parasitemia | Peak parasitemia | ||
Anemia | Parasitemia | ||||||
bvMSP142 in Freund's adjuvant | 2 | 4 | 1 | 0.019 | 0.004 | NS | 0.004 |
P30P2MSP119 in Freund's adjuvant | 0 | 3 | 4 | 0.029 | 0.029 | 0.015 | 0.029 |
bvMSP142 in MF59 | 0 | 0 | 7 | NS | NS | NS | NS |
P30P2MSP119 in MF59 | 0 | 0 | 7 | NS | NS | NS | NS |
Both antigens in Freund's adjuvant | NS | 0.009 | NS | 0.009 |
P values are for comparisons of groups receiving the individual vaccines to groups receiving the adjuvant only, except that P values for groups receiving both antigens represent comparisons of the immunized groups to each other. P values were determined with a nonparametric Mann-Whitney test. NS, not significant.