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. 2022 Dec 31;12:22650. doi: 10.1038/s41598-022-27008-x

Table 2.

Changes in lipid levels (mean and SD) from the third month to each time point among patients with different endocrine therapies.

TAM OFS + TAM OFS + AI
3 months 6 months 12 months 24 months 3 months 6 months 12 months 24 months 3 months 6 months 12 months 24 months
(baseline) (baseline) (baseline)
TC 4.60 ± 1.11 4.50 ± 1.00 4.53 ± 1.07 4.54 ± 1.01 4.55 ± 0.89 4.39 ± 0.80 4.45 ± 0.76 4.60 ± 0.86 4.88 ± 1.23 4.91 ± 0.88 5.10 ± 1.14 5.36 ± 1.15
(mmol/L) P = 0.088 P = 0.194 P = 0.308 P = 0.171 P = 0.416 P = 0.560 P = 0.866 P = 0.226 P = 0.017
TG 1.88 ± 1.63 1.91 ± 1.34 1.89 ± 1.74 1.74 ± 1.54 2.10 ± 1.56 1.79 ± 0.74 1.88 ± 1.20 1.82 ± 0.76 1.32 ± 0.50 1.25 ± 0.57 1.29 ± 0.45 1.13 ± 0.35
(mmol/L) P = 0.782 P = 0.971 P = 0.192 P = 0.091 P = 0.194 P = 0.105 P = 0.852 P = 0.927 P = 0.613
LDL-C 2.38 ± 0.92 2.25 ± 0.83 2.25 ± 0.88 2.19 ± 0.84 2.30 ± 0.71 2.22 ± 0.66 2.22 ± 0.62 2.23 ± 0.70 2.73 ± 0.89 2.88 ± 0.60 2.91 ± 0.81 3.01 ± 0.79
(mmol/L) P = 0.004 P = 0.004 P < 0.001 P = 0.356 P = 0.342 P = 0.337 P = 0.319 P = 0.194 P = 0.067
HDL-C 1.38 ± 0.32 1.40 ± 0.34 1.43 ± 0.32 1.51 ± 0.34 1.42 ± 0.34 1.43 ± 0.31 1.47 ± 0.32 1.51 ± 0.30 1.35 ± 0.24 1.35 ± 0.29 1.41 ± 0.31 1.47 ± 0.24
(mmol/L) P = 0.409 P = 0.018 P < 0.001 P = 0.767 P = 0.076 P = 0.015 P = 0.972 P = 0.360 P = 0.107

P value correspond to baseline (treated with endocrine therapy for 3 months).