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. 2022 Dec 31;12:22648. doi: 10.1038/s41598-022-27293-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation of CHD7-bound enhancer regions with transcription of target genes in hNCCs. (A) Boxplot showing expression of all genes (left) and hNCC-specific CHD7-target genes (right) in hiPSCs, hNECs, and hNCCs. (B) Correlation analysis of cell type-specific CHD7 target genes and DEGs in hiPSCs, hNECs, and hNCCs. Heatmap showing z-score of correlations.