Table 3.
Independent Variables Related to Primary Outcome (Logistic Regression)
| Clinical Parameters | Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|---|
| Odds Ratio | (95% Confidence Interval) | P value | Adjusted Odds Ratio | (95% Confidence Interval) | P value | |
| Female | 0.60 | (0.30–1.19) | 0.143 | |||
| Age | 1.02 | (0.998–1.04) | 0.086 | 1.01 | (0.99–1.03) | 0.267 |
| Diabetes mellitus | 2.52 | (1.21–5.24) | 0.012* | 1.58 | (0.68–3.65) | 0.284 |
| ICUs admission | 0.79 | (0.22–2.83) | 0.742 | |||
| Internal medicine service | 0.58 | (0.28–1.20) | 0.141 | |||
| APACHE II | 1.02 | (0.95–1.10) | 0.548 | |||
| Vancomycin samples | 1.22 | (0.73–2.04) | 0.453 | |||
| Creatinine clearance | 1.00 | (0.995–1.01) | 0.943 | |||
| Body mass index | 0.99 | (0.93–1.05) | 0.685 | |||
| Definite treatment | 1.06 | (0.53–2.13) | 0.868 | |||
| CVI method | 3.53 | (1.56–7.96) | 0.002* | 2.93 | (1.23–6.95) | 0.015* |
Note: *Statistically significant.
Abbreviations: APACHE II, Acute Physiology and Chronic Health Evaluation II; CVI, continuous vancomycin infusion; ICUs, intensive care units.