Skip to main content
. 2022 Dec 28;15:4065–4074. doi: 10.2147/DMSO.S379616

Table 2.

Glycemic Variability in the 1st Trimester in Pregnant Women with and without GDM (n=60)

CGM Parameters (n=60) GDM (n=10) Adjusted Median (IQR) Non-GDM (n=50) Adjusted Median (IQR) Adjusted p*
First trimester
Gestational age at CGM application (weeks), mean ± SD 11.1±1.2 11.1±1.4 0.93
Mean glucose (mmol/L) 4.43 (4.2–4.6) 4.07 (4.0–4.2) 0.20
J-Index 10.0 (8.8–10.4) 8.26 (7.1–9.8) 0.04
MAGE (mmol/L) 3.26 (3.2–3.3) 2.59 (2.4–2.6) 0.002
SD (mmol/L) 1.31 (1.27–1.32) 1.01 (0.95–1.02) 0.001
CV (%), adjusted mean ± SD 28.3±1.6 24.3±1.1 0.007
TIR (%), adjusted mean ± SD 68.9±5.4 69.2±3.9 0.51
TBR (%), adjusted mean ± SD 26.9±5.7 30.3±4.2 0.84
TAR (%) 4.30 (3.96–4.40) 0.59 (0.20–0.93) 0.05

Notes: *p values were adjusted for maternal pre-pregnancy BMI and ethnicity Data was expressed as adjusted median (interquartile range) unless otherwise stated. The p value significance is set at p<0.003.

Abbreviations: GDM, gestational diabetes mellitus; BMI, body mass index; CGM, continuous glucose monitoring; %CV, coefficient of variation; SD, standard deviation; MAGE, Mean amplitude of glycemic excursions; GA, gestational age; %TAR, percentage of time above target range; %TIR, percentage of time in range; %TBR, percentage of time below target range.