Table 2.
CGM Parameters (n=60) | GDM (n=10) Adjusted Median (IQR) | Non-GDM (n=50) Adjusted Median (IQR) | Adjusted p* |
---|---|---|---|
First trimester | |||
Gestational age at CGM application (weeks), mean ± SD | 11.1±1.2 | 11.1±1.4 | 0.93 |
Mean glucose (mmol/L) | 4.43 (4.2–4.6) | 4.07 (4.0–4.2) | 0.20 |
J-Index | 10.0 (8.8–10.4) | 8.26 (7.1–9.8) | 0.04 |
MAGE (mmol/L) | 3.26 (3.2–3.3) | 2.59 (2.4–2.6) | 0.002 |
SD (mmol/L) | 1.31 (1.27–1.32) | 1.01 (0.95–1.02) | 0.001 |
CV (%), adjusted mean ± SD | 28.3±1.6 | 24.3±1.1 | 0.007 |
TIR (%), adjusted mean ± SD | 68.9±5.4 | 69.2±3.9 | 0.51 |
TBR (%), adjusted mean ± SD | 26.9±5.7 | 30.3±4.2 | 0.84 |
TAR (%) | 4.30 (3.96–4.40) | 0.59 (0.20–0.93) | 0.05 |
Notes: *p values were adjusted for maternal pre-pregnancy BMI and ethnicity Data was expressed as adjusted median (interquartile range) unless otherwise stated. The p value significance is set at p<0.003.
Abbreviations: GDM, gestational diabetes mellitus; BMI, body mass index; CGM, continuous glucose monitoring; %CV, coefficient of variation; SD, standard deviation; MAGE, Mean amplitude of glycemic excursions; GA, gestational age; %TAR, percentage of time above target range; %TIR, percentage of time in range; %TBR, percentage of time below target range.