Fig. 4.

Representative OCT B-scans of macular drusen volume changes in PBM (A,B) and sham (C,D) subjects that completed all study treatments. A PBM subject with overall ETDRS drusen volume of 0.61 mm³ at baseline. B At end of study (month 10), the PBM subject showed a reduction in macular drusen volume to 0.56 mm³. C Sham subject with overall ETDRS drusen volume of 1.07 mm³ at baseline. D At end of study (month 10), the sham subject showed an increase in macular drusen volume to 1.10 mm³. Segmentation of Bruch’s membrane (red line) and the RPE (blue line). ETDRS early treatment diabetic retinopathy study, PBM photobiomodulation