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. 2022 Dec 19;10:989932. doi: 10.3389/fbioe.2022.989932

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Copyright © 2022 Goncharov, Kovalskaia, Romanishin, Shved, Belousov, Tiasto, Gulaia, Neergheen, Rummun, Liskovykh, Larionov, Kouprina and Kumeiko.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Micronuclei (MNi) formation 24 h after PLE treatment of HT1080 and RPE-1cells. (A) Examples of (MNi) formation in HT1080 and RPE-1 cells. White arrows point to the MNi. (B) The percentage of MNi after PLE treatment compared to untreated cells. Error bars correspond to a standard deviation (SD) of four replicates. Statistical analysis was performed using one-way ANNOVA, asterisks indicate statistical significance (*p < 0.05, **p < 0.01, relative to the negative control—untreated cells).