Table 1.
SNPs studied, genetic location, ancestral allele and MAF.
| RS | SNP | Location | Ancestral allele | Variation | MAF | Ref. life technologies® |
|---|---|---|---|---|---|---|
| VEGF-A | ||||||
| rs699947 | c.-2595A > C | Promoter | A | A > C | A = 0.344/752 | C_8311602_10 |
| rs2010963 | c.-634C > G | 5′UTR | G | C > G | C = 0.343/748 | C_8311614_10 |
| rs833061 | c.-1498C > T | Promoter | C | C > T | C = 0.380/828 | C_1647381_10 |
| rs3025039 | c.*237C > T | 3′UTR | C | C > T | T = 0.149/325 | C_16198794_10 |
| VEGFR-1 | ||||||
| rs9582036 | c.3635+319G > T | Intron 3 | C | A > C | C = 0.357/778 | C_1910658_10 |
| VEGFR-2 | ||||||
| rs2071559 | c.-906T > C | Promoter | T | C > T | G = 0.459/1000 | C15869271_10 |
| rs2305948 | c.889G > A | Exon 7 | C | C > T | T = 0.131/286 | C_22271999_20 |
| rs1870377 | c.1416A > T | Exon 11 | T | A > T | A = 0.235/511 | C_11895315_20 |
| HIF-1α | ||||||
| rs11549465 | c.1744C > T | Exon 13 | C | C > T | T = 0.073/160 | C_25473074_10 |
SNPs, single nucleotide polymorphism; MAF, minor allele frequency; VEGF, vascular endothelial growth factor; VEGFR, VEGF receptor.