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. 2022 Dec 22;19(12):1055–1068. doi: 10.30773/pi.2022.0174

Table 2.

Edges showing significantly decreased functional connectivity in individuals with autism spectrum disorder

Connectivity
Clinical correlation
ROI 1 ROI 2 p-value (FDR) ASD group
TD group
rho p % sub rho p % sub
Right, cingulate, dorsal area 23 Left, cingulate, dorsal area 23 <0.01 CARS 0.45 0.02 93.55 0.40 0.03 93.55
SRS Com 0.68 <0.01 54.84 0.00 >0.99 54.84
Right, precuneus, area 31 Left, precuneus, are 31 <0.01
Right, inferior parietal lobule, rostroventral area 40 Left, inferior frontal gyrus, caudal area 45 <0.01 SRS Com 0.68 <0.01 54.84 0.14 0.59 54.84
SRS Awa 0.52 0.03 54.84 0.27 0.29 54.84
SCI 0.52 0.03 54.84 0.19 0.47 54.84
Left, Inferior parietal lobule, rostroventral area 40 Right, superior frontal gyrus, medial area 9 <0.01
Left, inferior frontal gyrus, caudal area 45 <0.01 SRS Com 0.54 0.02 54.84 0.00 0.99 54.84
Right, superior temporal gyrus, rostral area 22 <0.01
Left, inferior temporal gyrus, ventrolateral area 37 <0.01

ASD group, children with autism spectrum disorder; Awa; social awareness; CARS, Childhood Autism Rating Scale; com; communication; FDR, false discovery rate; ROI, region of interest; SCI, Social Communications Index; SRS, Social Responsiveness Scale; TD group, children with typical development; % sub, the percentage of subjects who have clinical score