Table 2.
Edges showing significantly decreased functional connectivity in individuals with autism spectrum disorder
| Connectivity |
Clinical correlation |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| ROI 1 | ROI 2 | p-value (FDR) | ASD group |
TD group |
|||||
| rho | p | % sub | rho | p | % sub | ||||
| Right, cingulate, dorsal area 23 | Left, cingulate, dorsal area 23 | <0.01 | CARS | 0.45 | 0.02 | 93.55 | 0.40 | 0.03 | 93.55 |
| SRS Com | 0.68 | <0.01 | 54.84 | 0.00 | >0.99 | 54.84 | |||
| Right, precuneus, area 31 | Left, precuneus, are 31 | <0.01 | |||||||
| Right, inferior parietal lobule, rostroventral area 40 | Left, inferior frontal gyrus, caudal area 45 | <0.01 | SRS Com | 0.68 | <0.01 | 54.84 | 0.14 | 0.59 | 54.84 |
| SRS Awa | 0.52 | 0.03 | 54.84 | 0.27 | 0.29 | 54.84 | |||
| SCI | 0.52 | 0.03 | 54.84 | 0.19 | 0.47 | 54.84 | |||
| Left, Inferior parietal lobule, rostroventral area 40 | Right, superior frontal gyrus, medial area 9 | <0.01 | |||||||
| Left, inferior frontal gyrus, caudal area 45 | <0.01 | SRS Com | 0.54 | 0.02 | 54.84 | 0.00 | 0.99 | 54.84 | |
| Right, superior temporal gyrus, rostral area 22 | <0.01 | ||||||||
| Left, inferior temporal gyrus, ventrolateral area 37 | <0.01 | ||||||||
ASD group, children with autism spectrum disorder; Awa; social awareness; CARS, Childhood Autism Rating Scale; com; communication; FDR, false discovery rate; ROI, region of interest; SCI, Social Communications Index; SRS, Social Responsiveness Scale; TD group, children with typical development; % sub, the percentage of subjects who have clinical score