Table 3.

Areas showing significantly decreased local/nodal efficiency in individuals with autism spectrum disorder

Network measure	ROI	p-value (FDR corrected)
Local efficiency
	Left, cingulate gyrus, subgenual area 32	<0.05 FWER
	Left, inferior frontal gyrus, caudal area 45	<0.05 FWER
Nodal efficiency
Frontal lobe	Right, superior frontal gyrus, dorsolateral area 8	<0.01
	Right, superior frontal gyrus, lateral area 9	<0.05
	Right, superior frontal gyrus, medial area 9	<0.05
	Right, superior frontal gyrus, medial area 10	<0.05
	Left, superior frontal gyrus, medial area 10	<0.05
	Left, superior frontal gyrus, medial area 9	<0.05
	Right, middle frontal gyrus, inferior frontal junction	<0.05
	Right, middle frontal gyrus ventral area 9/46	<0.05
	Left, middle frontal gyrus ventral area 9/46	<0.05
	Right, inferior frontal gyrus, inferior frontal sulcus	<0.05
	Right, inferior frontal gyrus, caudal area 45	<0.05
	Right, inferior frontal gyrus, ventral area 44	<0.01
	Left, Inferior frontal gyrus, ventral area 44	<0.05
	Left, inferior frontal gyrus, caudal area 45	<0.05 FWER
	Right, precentral gyrus, area 4 (head and face region)	<0.01
	Right, precentral gyrus, area 4 (upper limb region)	<0.01
	Right, precentral gyrus, area 4 (tongue and larynx region)	<0.01
	Right, precentral gyrus, caudal ventrolateral area 6	<0.05
	Left, precentral gyrus, caudal ventrolateral area 6	<0.05
	Left, precentral gyrus, area 4 (tongue and larynx region)	<0.05
Temporal lobe	Right, superior temporal gyrus, area 41/42	<0.01
	Right, superior temporal gyrus, caudal area 22	<0.05
	Right, superior temporal gyrus, rostral area 22	<0.05
	Left, middle temporal gyrus, dorsolateral area 37	<0.05
	Left, inferior temporal gyrus, caudolateral of area 20	<0.05
	Right, superior temporal sulcus, rostroposterior	<0.05
Parietal lobe	Right, superior parietal lobule, rostral area 7	<0.05
	Right, superior parietal lobule, caudal area 7	<0.01
	Right, superior parietal lobule, lateral area 5	<0.05 FWER
	Right, superior parietal lobule, postcentral area 7	<0.05 FWER
	Right, superior parietal lobule, intraparietal area 7	<0.01
	Left, superior parietal lobule, intraparietal area 7	<0.05 FWER
	Left, superior parietal lobule, postcentral area 7	<0.01
	Left, superior parietal lobule, lateral area 5	<0.05 FWER
	Left, superior parietal lobule, caudal area 7	<0.05 FWER
	Left, Superior parietal lobule, rostral area 7	<0.01
	Right, Inferior parietal lobule, rostrodorsal area 39	<0.05
	Right, Inferior parietal lobule, rostrodorsal area 40	<0.01
	Right, inferior parietal lobule, rostroventral area 40	<0.01
	Left, inferior parietal lobule, rostroventral area 40	<0.01
	Left, inferior parietal lobule, rostroventral area 39	<0.01
	Left, inferior parietal lobule, rostrodorsal area 40	<0.05
	Right, precuneus, medial area 7	<0.05
	Right, precuneus, area 31	<0.01
	Left, precuneus, area 31	<0.05
	Left, precuneus, medial area 7	<0.05
	Right, postcentral gyrus, area 1/2/3 (upper limb, head and face region)	<0.05
	Right, postcentral gyrus, area 1/2/3 (tongue and larynx region)	<0.05
	FWER Right, postcentral gyrus, area 2	<0.05
	Right, postcentral gyrus, area 1/2/3 (trunk region)	<0.05
	Left, postcentral gyrus, area 2	<0.01
	Left, postcentral gyrus, area 1/2/3 (tongue and larynx region)	<0.01
	Left, postcentral gyrus, area 1/2/3 (upper limb, head and face region)	<0.05
Insula	Right, insula, hypergranular insula	<0.05
	Right, insula, dorsal granular insula	<0.01
	Left, insula, dorsal granular insula	<0.05
	Left, hypergranular insula	<0.05
Cingulate	Right, cingulate gyrus, dorsal area 23	<0.05
	Right, cingulate gyrus, subgenual area 32	<0.05
	Left, cingulate gyrus, subgenual area 32	<0.05
Occipital	Right, lateral occipital, medial superior occipital gyrus	<0.05
	Right, lateral occipital, lateral superior occipital gyrus	<0.05 FWER
	Left, lateral occipital, lateral superior occipital gyrus	<0.05 FWER
	Left, lateral occipital, medial superior occipital gyrus	<0.05
Cerebellum	Cerebellar crus II	<0.05

FDR, false discovery rate; FWER, family-wise error rate; ROI, region of interest