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. 2023 Jan 1;27(1):105–112. doi: 10.4196/kjpp.2023.27.1.105

Fig. 3. Effects of sericin and I-sericin or fibroin and I-fibroin on inflammatory markers in H2O2-treated HaCaT cells.

Fig. 3

(A) COX-2 expression of HaCaT cell with (A1) sericin or I-sericin and (A2) fibroin or I-fibroin pretreatment followed by H2O2; (B) iNOS expression of HaCaT cell with (B1) sericin or I-sericin and (B2) fibroin or I-fibroin pretreatment followed by H2O2; (C) IL-1β concentration of of HaCaT cell with (C1) sericin or I-sericin and (C2) fibroin or I-fibroin pretreatment followed by H2O2; (D) TNF-α concentration of HaCaT cell with (D1) sericin or I-sericin and (D2) fibroin or I-fibroin pretreatment followed by H2O2. COX-2, cyclooxygenase-2; iNOS, inducible nitric oxide synthase; IL, interleukin; TNF, tumor necrosis factor. Different label means a significant difference between each group by one-way ANOVA. **p < 0.01, and ***p < 0.005 compared to control. #p < 0.05, ##p < 0.01, and ###p < 0.005 compared with H2O2-treated only. $p < 0.05, compared to the sericin or fibroin-treated group.