Fig. 6.

Functional decellularized extracellular matrix in the Cardiac repair. (A) Whole heart perfusion decellularization experiment in rats. (i) Gross view of whole heart decellularization in rats, H&E staining, and immunofluorescence images. (ii)Sections of decellularized rat hearts stained with immunofluorescence did not detect nuclei or contractile proteins. (iii) Analysis of the histology and electron micrographs of recellularized rat heart constructs. Adapted reprinted with permission from Ref. [8] (License number:5,442,460,220,568) (B) Natural myocardial and decellularized myocardial scaffolds. (i)Morphology of natural myocardium and decellularized myocardial scaffolds. (ii)H&E staining of the stent after decellularization and the H&E staining of the stent after two weeks and four weeks of recellularization. Adapted reprinted with permission from Ref. [278] (License number:5,442,470,287,789).