Table 5.
Multivariable logistic regression model for preoperative variables associated with upstaging on pathology for patients with organ-confined disease on mpMRI
| Parameter | OR (95% CI) | p value |
|---|---|---|
| mpMRI criteria | ||
| Imaging quality (vs PI-QUAL 3) | 0.012 | |
| PI-QUAL 1–2 | 3.4 (1.2–9.3) | 0.020 |
| PI-QUAL 4–5 | 1.02 (0.5–2.3) | 0.943 |
| Multiple foci on mpMRI | 3.2 (1.8–5.9) | 0.000 |
| Base location for the index lesion | 2.3 (1.3–4.3) | 0.006 |
| Early extraprostatic extension | 2.4 (1.3–4.4) | 0.006 |
| Biopsy criteria | ||
| Percentage of targeted positive cores (per 20% increment) | 1.22 (1.0–1.5) | 0.036 |
| Percentage of systematic positive cores (per 20% increment) | 1.32 (1.0–1.7) | 0.027 |
| Constanta | 0.03 (0.01–0.08) | <0.001 |
CI = confidence interval; mpMRI = multiparametric magnetic resonance imaging; OR = odds ratio; PI-QUAL = Prostate Imaging Quality score (nondiagnostic, PI-QUAL 1–2; sufficient, PI-QUAL 3; optimal, PI-QUAL 4–5).
a
Residual from the multivariable analysis.