Table 2.
Sleep variables found in participants taking bupropion alone or bupropion in combination with SSRIs.
| Bupropion (n = 6) | Bupropion + SSRIs (n = 6) | Mann–Whitney U Test | |
|---|---|---|---|
| Median (IQR) | Median (IQR) | P < | |
| Time in bed, min | 486.8 (480.0–512.0) | 520.7 (489.0–525.5) | NS |
| Sleep period time, min | 475.8 (432.5–493.5) | 493.0 (478.0–510.0) | NS |
| Total sleep time, min | 401.0 (321.0–432.0) | 419.5 (288.0–469.0) | NS |
| Sleep latency, min | 14.8 (5.5–19.0) | 11.5 (10.5–14.5) | NS |
| Stage R latency, min | 76.3 (57.5–94.0) | 93.7 (89.5–96.0) | NS |
| Stage shifts/h | 12.0 (8.8–15.3) | 14.3 (8.3–20.1) | NS |
| Awakenings/h | 5.1 (4.6–5.5) | 4.6 (3.4–5.7) | NS |
| Sleep efficiency, % | 85.1 (78.4–88.1) | 83.2 (55.7–95.2) | NS |
| Stage W, % | 11.2 (5.9–21.5) | 14.8 (2.9–43.1) | NS |
| Stage N1, % | 8.6 (4.0–9.7) | 9.3 (3.9–16.9) | NS |
| Stage N2, % | 39.1 (36.9–58.0) | 36.1 (31.9–42.1) | NS |
| Stage N3, % | 12.6 (10.2–16.9) | 24.3 (13.1–27.6) | NS |
| Stage R, % | 19.8 (16.3–21.9) | 7.7 (6.7–16.0) | NS |
IQR = interquartile range, SSRIs, selective serotonin reuptake inhibitors.