Table 4.
Leg movement activity during sleep measures found in participants taking bupropion alone or bupropion associated with SSRIs.
| Bupropion (n = 5) | Bupropion + SSRIs (n = 5) | Mann–Whitney U Test | |
|---|---|---|---|
| Median (IQR) | Median (IQR) | P < | |
| PLMS index, n/h | 0.5 (0.0–1.6) | 3.4 (1.0–4.3) | NS |
| SILMS index, n/h | 5.1 (3.0–6.1) | 2.0 (1.4–2.1) | NS |
| ISOLMS index, n/h | 11.8 (9.5–13.6) | 8.9 (5.7–10.2) | NS |
| Total LMS index, n/h | 16.9 (14.6–19.7) | 10.9 (9.6–19.1) | NS |
| Bilateral PLMS, % | 0.2 (0.0–0.3) | 0.8 (0.6–2.5) | NS |
| Periodicity index | 0.047 (0.000–0.048) | 0.129 (0.092–0.356) | NS |
| PLMS duration, s | 2.3 (1.2–3.1) | 2.2 (1.7–3.0) | NS |
| SILMS duration, s | 2.3 (1.9–2.9) | 2.8 (2.3–2.9) | NS |
| ISOLMS duration, s | 2.5 (2.1–3.3) | 3.0 (2.3–3.4) | NS |
| REM sleep PLMS index, n/h | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | NS |
| NREM sleep PLMS index, n/h | 0.6 (0.0–1.7) | 3.7 (1.4–4.4) | NS |
IQR = interquartile range, ISOLMS = isolated leg movements during sleep, LMS = leg movements during sleep, NREM = nonrapid eye movement, PLMS = periodic leg movements during sleep, REM = rapid eye movement, SILMS = short-interval leg movements during sleep, SSRIs = selective serotonin reuptake inhibitors.