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. 2023 Jan 2;13:34. doi: 10.1038/s41598-022-26202-1

Table 1.

The optimal cut-off value of SARS-CoV-2 Quant II using the SARS-CoV-2 NeutraLISA as a reference standard.

SARS-CoV-2 Quant II (BAU/mL) NAb (% inhibition) % Agreement Kappa (95% CI) p-value Sensitivity (95% CI) Specificity (95% CI)
 < 35  ≥ 35 96.1 0.91 (0.86, 0.96)  < 0.001 0.96 (0.93, 0.98) 0.96 (0.90, 0.99)
 < 83.9 93 8
 ≥ 83.9 4 200
 < 80  ≥ 80 98.4 0.97 (0.94, 1)  < 0.001 0.99 (0.95, 1) 0.98 (0.94,1)
 < 210.8 146 2
 ≥ 210.8 3 154
 < 85  ≥ 85 99.3 0.99 (0.97, 1)  < 0.001 1.00 (0.98, 1) 0.99 (0.95, 1)
 < 261.9 151 0
 ≥ 261.9 2 152
 < 90  ≥ 90 99.3 0.99 (0.97, 1)  < 0.001 0.99 (0.95, 1) 1.00 (0.98, 1)
 < 442.7 155 2
 ≥ 442.7 0 148
 < 95  ≥ 95 99.7 0.99 (0.98, 1)  < 0.001 0.99 (0.96, 1) 1.00 (0.98, 1)
 < 442.7 156 1
 ≥ 442.7 0 148