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. Author manuscript; available in PMC: 2023 Jan 2.
Published in final edited form as: Brain Stimul. 2022 Dec 7;15(6):1552–1564. doi: 10.1016/j.brs.2022.12.003

Fig. 5. Correlation of FUS dose – fMRI responses between target and off-target regions in resting and activation states.

Fig. 5.

(A) Plots of peak BOLD signal changes at the FUS-targeted area 3a/3b and seven off-target regions in response to FUS stimulation at three FUS intensities (h: high, m: medium, l: low) during FUS alone (red curves) and simultaneous FUS + Tactile (green curves) stimulation. (B) Plots of % BOLD signal differences between simultaneous FUS + tactile and tactile stimulation conditions (set as 100%) at each region. (C-D) Ca & Da: plots of BOLD signal changes at three FUS intensities across all regions at rest (Ca, FUS-alone condition) and activation (Da, FUS + tactile condition) states. Cb & Db: plots of correlation (r values) between area 3a/3b and each of the off-target regions. E: plots of % BOLD signal changes across all regions in response to tactile stimulation at left hand digits.