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. 2023 Jan 2;42:2. doi: 10.1186/s13046-022-02584-y

Table 2.

DEGs of MHC II locus

D374Y Q152H
Gene Description log2(FC) P-adj log2(FC) P-adj
H2-DMa H2i, class II, locus DMa 5.86 2.48E-73 2.99 2.99E-60
H2-Eb2 H2, class II antigen E beta2 5.696 2.57E-27 1.71 1.11E-12
H2-Aa H2, class II antigen A, alpha 5.596 8.44E-43 1.07 1.02E-05
H2-Eb1 H2, class II antigen E beta 5.48 1.49E-42 1.28 2.47E-07
H2-Ab1 H2, class II antigen A, beta 1 5.23 4.31E-41 1.46 3.88E-09
H2-DMb1 H2, class II, locus Mb1 4.86 1.16E-76 1.54 3.81E-10
H2-Q7 H2, Q region locus 7 4.17 2.26E-47 1.41 3.57E-09
H2-Q6 H2, Q region locus 6 4.11 6.37E-22 1.38 4.97E-08
H2-T10 H2, T region locus 10 3.68 1.45E-52 1.16 5.98E-06
H2-M3 H2, M region locus 3 3.50 1.44E-36 2.10 4.26E-26
H2-T23 H2, T region locus 23 3.42 2.00E-65 1.53 2.17E-31
H2-K1 H2, K1, K region 3.24 6.42E-66 1.25 9.00E-08
H2-M2 H2, M region locus 2 3.02 2.32E-05
H2-D1 H2, D region locus 1 2.94 1.26E-80 1.14 1.09E-06
H2-DMb2 H2, class II, locus Mb2 2.90 1.30E-07
H2-T9 H2, T region locus 9 2.74 3.58E-15
H2-Q4 H2, Q region locus 4 2.71 4.05E-81 0.89 5.03E-09
H2-T22 H2, T region locus 22 2.22 2.31E-50 0.67 6.94E-05
H2-Q10 H2, Q region locus 10 2.20 0.0003479
H2-Q2 H2, Q region locus 2 2.12 0.0033861
H2-Q1 H2, Q region locus 1 1.95 0.0117126
H2-Bl H2, blastocyst 1.71 0.0426706
H2-Ob H2, O region beta locus 1.65 8.58E-05
H2-Oa H2, O region alpha locus 1.55 0.0215398
H2-T24 H2, T region locus 24 1.14 0.0351915

i: histocompatibility 2