Table 3.

Secondary Endpoint Results

Parameter	D0	D28	Units	% Variation
Wrinkle depth	344.6 ± 25.9	284.7 ± 20.1 **	mm	−15.8%
Skin smoothness, Sa	38.2 ± 1.6	35.7 ± 1.7 *	mm	−6.3%
Skin moisturization	59.4 ± 1.3	66.1 ± 1.1 ***	cu	+11.7%
Skin elasticity
R0 (skin distensibility)	0.2916 ± 0.091	0.2661 ± 0.0100 ***	mm	−8.9%
R2 (overall elasticity)	0.4957 ± 0.0146	0.5466 ± 0.0165 ***	%	+10.4%
Skin radiance	11.4 ± 0.6	13.0 ± 0.3 ***	au	+16.3%

Notes: Data are average (± standard error). The statistical analysis (D28 vs D0) is reported as follows: * p<0.05, ** p<0.01, and ***p<0.005. D0 baseline. D28 follow-up visit after 28 days of product use. au arbitrary units. cu corneometric units.