Table 5.
Comparison of Characteristics Between Patients Who Had ABPA with or Without Central Bronchiectasis
| Central Bronchiectasis | P value | ||
|---|---|---|---|
| Yes (n=16) | No (n=45) | ||
| Age, years | 50.94±19.06 | 58.60±17.35 | 0.145 |
| Male | 5(31.25%) | 26(57.78%) | 0.068 |
| Smokers | 1(6.25%) | 20(44.44%) | 0.006 |
| Pack-years of smoking | 0(0–0) | 0(0–18.75) | 0.025 |
| Dead | 1(6.25%) | 10(22.22%) | 0.294 |
| Duration of ABPA, in months | 592(105.00–631.00) | 154.5(73.00–427.50) | 0.018 |
| BMI (kg/m2) | 20.75±3.29 | 23.38±3.27 | 0.009 |
| Peripheral blood cells | |||
| Leukocyte, ×109/L | 9.50±3.32 | 8.78±3.95 | 0.522 |
| Neutrophil, ×109/L | 5.46±2.84 | 5.57±3.21 | 0.899 |
| Neutrophil, % | 54.82±18.72 | 58.58±18.09 | 0.498 |
| Eosinophil, ×109/L | 0.77(0.23–0.94) | 0.48(0.05–0.71) | 0.029 |
| Eosinophil, % | 9.6(2.61–11.15) | 6.4(0.45–13.97) | 0.144 |
| Inflammatory indicator | |||
| NLR | 1.90(1.21–3.99) | 4.14(1.5–7.71) | 0.375 |
| CRP, mg/L | 3.94(2.25–11.70) | 8.09(1.23–41.37) | 0.910 |
| ESR, mm/h | 26.00(17.00–29.00) | 12.00(5.25–28.75) | 0.160 |
| Immunological tests | |||
| Total IgE, IU/mL | 2248.00(1011.00–2500.00) | 2322.00(1262.75–2500.00) | 0.398 |
| Sp-IgE, kUA/L | 13.30(3.50–25.9) | 0.93(0.54–6.10) | 0.001 |
| Comorbidity | |||
| Asthma | 15(93.75%) | 37(82.22%) | 0.480 |
| COPD | 1(6.25%) | 9(20.00%) | 0.377 |
| Allergic rhinitis | 8(50.00%) | 24(53.33%) | 0.819 |
| Spirometry | |||
| FEV1/FVC | 54.44±18.95 | 62.64±14.77 | 0.112 |
| FEV1/pred | 50.78±29.71 | 62.97±24.54 | 0.153 |
| PEF, L/s | 3.16(2.82–6.52) | 3.90(3.16–5.75) | 0.078 |
| PEF, % | 49.50(38.20–94.2) | 65.25(43.33–87.08) | 0.160 |
| DLCO, % | 66.68±31.97 | 74.10±18.19 | 0.317 |
| DLCO/VA, mmol/min/kPa/L | 1.48(1.17–1.60) | 1.24(1.04–1.55) | 0.616 |
| Arterial blood gas | |||
| PaO2, mmHg | 75.21±13.57 | 75.78±12.21 | 0.889 |
| PaCO2, mmHg | 41.00(40.00–52.00) | 41(38.00–43.00) | 0.101 |
| SaO2, % | 95.00(94.00–97.00) | 96.00(94.00–97.00) | 0.866 |
| Treatment | |||
| Glucocorticoids | 15(93.75%) | 39(86.67%) | 0.759 |
| Antifungal Drugs | 13(81.25%) | 28(62.22%) | 0.164 |
Abbreviations: BMI, Body mass index; CRP, C-reactive protein; DLCO, Diffusion capacity of carbon monoxide; VA, Alveolar volume; ESR, Erythrocyte sedimentation rate; FEV1/FVC, Forced expiratory volume in one second (FEV1)/forced vital capacity (FVC); FEV1/pred, Percentage of FEV1 predicted; IgE, Immunoglobulin E; NLR, Neutrophil-to-lymphocyte ratio; PEF, Peak expiratory flow percentage; PaO2, Partial arterial oxygen pressure; PaCO2, Partial arterial pressure of carbon dioxide; SaO2, Oxygen saturation; Sp-IgE, Aspergillus fumigatus specific IgE.