Table 6.
C‐index and 95% CI of the Nomogram and Staging Systems (OS)
| Score | C-Index | |||||
|---|---|---|---|---|---|---|
| Training Cohort | P | Internal Validation Cohort | P | External Validation Cohort | P | |
| nomogram | 0.81 (0.79–0.83) | —— | 0.78 (0.75–0.81) | —— | 0.81 (0.79–0.83) | —— |
| AJCC | 0.63 (0.61–0.65) | <0.001 | 0.62 (0.59–0.65) | <0.001 | 0.67 (0.65–0.68) | <0.001 |
| Okuda | 0.61 (0.60–0.62) | <0.001 | 0.60 (0.58–0.62) | <0.001 | 0.60 (0.59–0.61) | <0.001 |
| JIS | 0.65 (0.63–0.67) | <0.001 | 0.63 (0.60–0.66) | <0.001 | 0.64 (0.62–0.66) | <0.001 |
| CLIP | 0.66 (0.64–0.69) | <0.001 | 0.66 (0.63–0.69) | <0.001 | 0.64 (0.62–0.66) | <0.001 |
| BCLC | 0.54 (0.52–0.56) | <0.001 | 0.51 (0.49–0.53) | <0.001 | 0.53 (0.53–0.54) | <0.001 |
Abbreviations: AJCC 7th, the American Joint Committee on Cancer seventh edition; BCLC, Barcelona Clinic Liver Cancer; mCLIP, Modified Cancer of the Liver Italian Program; JIS, Japan Integrated Staging Score.