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. 2022 Dec 13;32(12):1439–1470. doi: 10.1089/thy.2022.0251

Table 2.

Characteristics of High-Risk Thyroid Eye Disease Patients

Background
 Male sex
 Age >50 years
 Tobacco smoker
History
 Unstable thyroid function
 Diabetes mellitus
 Radioiodine in the past 6 months
 Progressive symptoms and/or signs of TED
 Orbital aching
 Diplopia
Examination
 Marked soft tissue inflammatory features
 Lagophthalmos (Fig. 2a)
 Impaired ocular motility, particularly elevation

The features outlined are associated with an increased probability of developing sight-threatening TED.24