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. Author manuscript; available in PMC: 2023 Apr 20.
Published in final edited form as: N Engl J Med. 2022 Oct 20;387(16):1522–1524. doi: 10.1056/NEJMc2210365

Figure 1. Estimated Mean Change in the PHQ-9 Score for Depressive Symptoms during Physician Internship, According to Weekly Work-Hour Levels, among 17,082 Participants in the Intern Health Study, 2009–2020.

Figure 1.

Scores on the Patient Health Questionnaire 9-item version (PHQ-9) were assessed at baseline (1 to 2 months before the start of the internship) and then quarterly throughout the internship year. On the PHQ-9, depression is categorized as minimal by a score of 0 to 4, mild by a score of 5 to 9, moderate by a score of 10 to 14, moderately severe by a score of 15 to 19, and severe by a score of 20 to 27. The widths of the 95% confidence intervals (I bars) have not been adjusted for multiplicity and may not be used in place of hypothesis testing. The analysis was adjusted for the baseline factors of sex, surgical or nonsurgical specialty, personality trait of neuroticism, history of depression before the internship, early family environment, age, cohort calendar year, marital status, parental status, and time-varying factors of stressful life events and medical errors (see the Supplementary Appendix for details of measures).