Table 1.
Clinical and metabolic characteristics of participants
| Clinical variable | NGT (n=5) | IGT (n=9) | Type 2 diabetes (n=4) | p value |
|---|---|---|---|---|
| Age | 67.2 ± 19.9 | 67.1 ± 10.2 | 69.7 ± 5.43 | 0.90 |
| Sex (M:F) | 2:3 | 3:6 | 1:3 | |
| BMI (kg/m2) | 26.3 ± 2.83 | 25.3 ± 3.63 | 24.7 ± 4.46 | 0.88 |
| HbA1c (mmol/mol) | 40.2 ± 4.97 | 40.5 ± 2.08 | 48.0 ± 9.17 | 0.35 |
| HbA1c (%) | 5.82 ± 0.49 | 5.80 ± 0.16 | 6.58 ± 0.79 | 0.24 |
| Total cholesterol (mmol/l) | 4.25 ± 0.16 | 5.18 ± 1.30 | 4.89 ± 1.27 | 0.37 |
| HDL-cholesterol (mmol/l) | 1.01 ± 0.34 | 1.28 ± 0.34 | 1.05 ± 0.46 | 0.38 |
| LDL-cholesterol (mmol/l) | 3.0 ± 1.35 | 3.47 ± 0.91 | 2.95 ± 1.07 | 0.74 |
| Triglycerides (mmol/l) | 1.39 ± 0.49 | 1.54 ± 0.66 | 1.97 ± 0.77 | 0.13 |
| Fasting glucose (mmol/l) | 4.77 ± 0.99 | 5.1 ± 0.47 | 8.3 ± 2.95 | 0.02 |
| Fasting insulin (pmol/l) | 39.2 ± 15.1 | 77.0 ± 45.6 | 127.7 ± 77.7 | 0.02 |
| Fasting C-peptide (ng/ml) | 1.48 ± 0.76 | 1.67 ± 0.72 | 2.13 ± 1.65 | 0.13 |
| Proinsulin/insulin ratio | 0.28 ± 0.16 | 0.32 ± 0.06 | 1.28 ± 0.50 | <0.01 |
| Diabetes duration | – | – | 4.00 ± 3.93 |
Data are presented as means ± SD
Living donors were classified according to their glucose tolerance before surgery into NGT (n=5), IGT (n=9) and type 2 diabetes (n=4)
p<0.05 is considered statistically significant
M:F, male:female