Table 4.

Asian proportion estimates overall, by phase, multi-institutional status, tier assessment, masking, and year.

	Frequency (%), studies	Total number of participants	Estimated proportion (95% CI)	P-value compared to reference category (*)	P-value compared to 2010 Census proportion (91.3%)	$I^2$(%)
Asian
Overall	–	–	1.27% (1.13–1.42)	–	< 0.0001	91.3%
Phase
II*	1094 (68.9%)	103,813	1.27% (1.10–1.45)	–	< .0001	91.3%
III	495 (31.2%)	220,155	1.27% (1.04–1.52)	0.979	< .0001
Institution status
Single*	682 (42.9%)	102,520	1.18% (0.96–1.41)	–	< .0001	91.2%
Multi-institutional	907 (57.1%)	221,448	1.33% (1.15–1.52)	0.308	< .0001
Tier assessment
1*	824 (51.9%)	57,943	1.05% (0.87–1.26)	–	< .0001	91.2%
2	765 (48.1%)	266,025	1.47% (1.27–1.68)	0.0045	< .0001
Masking
No masking*	341 (21.5%)	55,000	1.16% (0.88–1.47)	–	< .0001	91.0%
Single	107 (6.73%)	22,081	0.78% (0.40–1.28)	0.218	< .0001
Double	389 (24.5%)	79,017	1.50% (1.20–1.83)	0.119	< .0001
Triple	287 (18.1%)	72,527	1.65% (1.29–2.05)	0.0447	< .0001
Quadruple	465 (29.3%)	95,343	1.08% (0.85–1.34)	0.709	< .0001
Study start year
2008*	121 (7.61%)	35,685	1.19% (0.75–1.73)	–	< .0001	90.8%
2009	156 (9.82%)	30,239	0.95% (0.60–1.38)	0.438	< .0001
2010	134 (8.43%)	45,381	0.81% (0.47–1.25)	0.226	< .0001
2011	145 (9.13%)	17,765	0.88% (0.53–1.32)	0.332	< .0001
2012	159 (10.0%)	29,668	1.37% (0.94–1.88)	0.616	< .0001
2013	189 (11.9%)	32,347	1.24% (0.86–1.69)	0.534	< .0001
2014	169 (10.6%)	25,349	1.32% (0.91–1.80)	0.715	< .0001
2015	177 (11.1%)	29,085	1.45% (1.02–1.95)	0.460	< .0001
2016	150 (9.44%)	41,432	1.65% (1.17–2.20)	0.216	< .0001
2017	128 (8.06%)	23,619	1.96% (1.38–2.64)	0.0585	< .0001
2018	47 (2.96%)	10,243	1.57% (0.78–2.62)	0.465	< .0001
2019	14 (0.88%)	3155	1.55% (0.30–3.77)	0.683	0.0051