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. 2023 Jan 2;13:42. doi: 10.1038/s41598-022-23664-1

Table 6.

Black proportion estimates overall, by phase, multi-institutional status, tier assessment, masking, and year.

Frequency (%), studies Total number of participants Estimated proportion (95% CI) P-value compared to reference category (*) P-value compared to
2010 Census proportion (12.3%)
I2(%)
Black
Overall 17.0% (15.9–18.1)  < 0.0001 98.3%
Phase
II* 1094 (68.9%) 103,813 16.5% (15.3–17.8)  < .0001 98.3%
III 495 (31.2%) 220,155 18.0% (16.1–19.9) 0.220  < .0001
Institution status
Single* 682 (42.9%) 102,520 19.4% (17.7–21.2)  < .0001 98.3%
Multi-institutional 907 (57.1%) 221,448 15.3% (14.0–16.7) 0.0002  < .0001
Tier assessment
1* 824 (51.9%) 57,943 17.9% (16.4–19.5)  < .0001 98.3%
2 765 (48.1%) 266,025 16.1% (14.6–17.6) 0.091  < .0001
Masking
No masking* 341 (21.5%) 55,000 13.9% (11.8–16.1)  < .0001 98.3%
Single 107 (6.73%) 22,081 22.4% (18.1–27.1) 0.0005  < .0001
Double 389 (24.5%) 79,017 16.2% (14.1–18.4) 0.130  < .0001
Triple 287 (18.1%) 72,527 18.5% (16.0–21.1) 0.0065  < .0001
Quadruple 465 (29.3%) 95,343 17.9% (15.9–19.9) 0.0077  < .0001
Study start year
2008* 121 (7.61%) 35,685 13.7% (10.4–17.4) 0.200 98.2%
2009 156 (9.82%) 30,239 14.5% (11.5–17.8) 0.738 0.0500
2010 134 (8.43%) 45,381 21.0% (17.2–25.0) 0.0070  < .0001
2011 145 (9.13%) 17,765 22.5% (18.8–26.5) 0.0010  < .0001
2012 159 (10.0%) 29,668 17.3% (14.0–20.7) 0.155 0.0003
2013 189 (11.9%) 32,347 15.1% (12.3–18.2) 0.545 0.0107
2014 169 (10.6%) 25,349 18.6% (15.4–22.1) 0.0495  < .0001
2015 177 (11.1%) 29,085 14.5% (11.6–17.6) 0.749 0.0427
2016 150 (9.44%) 41,432 14.5% (11.4–17.8) 0.753 0.0584
2017 128 (8.06%) 23,619 19.1% (15.3–23.2) 0.0441  < .0001
2018 47 (2.96%) 10,243 20.7% (14.5–27.7) 0.0584 0.0026
2019 14 (0.88%) 3155 15.8% (6.31–28.2) 0.719 0.419