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. 2023 Jan 2;13:42. doi: 10.1038/s41598-022-23664-1

Table 7.

White proportion estimates overall, by phase, multi-institutional status, tier assessment, masking, and year.

Frequency (%), studies Total number of participants Estimated proportion (95% CI) P-value compared to reference category (*) P-value compared to
2010 Census proportion (79.8%)
I2(%)
White
Overall 77.6% (76.4–78.8)  < 0.0001 98.4%
Phase
II* 1094 (68.9%) 103,813 78.0% (76.6–79.5) 0.0007 98.4%
III 495 (31.2%) 220,155 76.7% (74.5–78.8) 0.31 0.0004
Institution status
Single* 682 (42.9%) 102,520 74.1% (72.2–76.1)  < .0001 98.4%
Multi-institutional 907 (57.1%) 221,448 80.0% (78.5–81.5)  < .0001 0.515
Tier assessment
1* 824 (51.9%) 57,943 76.5% (74.8–78.2)  < .0001 98.4%
2 765 (48.1%) 266,025 78.7% (77.0–80.4) 0.076 0.0338
Masking
No masking* 341 (21.5%) 55,000 81.6% (79.1–83.9) 0.396 98.3%
Single 107 (6.73%) 22,081 71.8% (66.7–76.6) 0.0003 0.0003
Double 389 (24.5%) 79,017 78.7% (76.3–81.0) 0.102 0.136
Triple 287 (18.1%) 72,527 74.0% (71.0–76.9) 0.0001  < .0001
Quadruple 465 (29.3%) 95,343 77.2% (75.0–79.4) 0.0103 0.0031
Study start year
2008* 121 (7.61%) 35,685 81.7% (77.5–85.5) 0.568 98.3%
2009 156 (9.82%) 30,239 81.1% (77.4–84.5) 0.828 0.750
2010 134 (8.43%) 45,381 73.9% (69.5–78.1) 0.0098 0.0017
2011 145 (9.13%) 17,765 72.5% (68.2–76.6) 0.0021 0.0001
2012 159 (10.0%) 29,668 77.3% (73.4–81.0) 0.122 0.0910
2013 189 (11.9%) 32,347 79.9% (76.5–83.2) 0.511 0.734
2014 169 (10.6%) 25,349 75.6% (71.7–79.3) 0.0316 0.0082
2015 177 (11.1%) 29,085 79.3% (75.7–82.7) 0.386 0.505
2016 150 (9.44%) 41,432 80.4% (76.5–83.9) 0.637 0.942
2017 128 (8.06%) 23,619 74.1% (69.6–78.4) 0.0136 0.0033
2018 47 (2.96%) 10,243 72.7% (65.0–79.8) 0.0321 0.0304
2019 14 (0.88%) 3155 79.4% (65.8–90.4) 0.731 0.864