Table 1.
Before matching | After matching | |||||
---|---|---|---|---|---|---|
All HD patients | All PD patients | p value | Matched HD patients | Matched PD patients | di | |
Number of patients | 81,116 | 6298 | 6296 | 6296 | ||
Age, mean (SD) | 61.51 (14.06) | 53.36 (15.03) | < 0.0001 | 52.89 (15.04) | 53.37 (15.03) | 3.24 |
Age group, no. (%) | ||||||
18–34 years | 3081 (3.80) | 747 (11.86) | < 0.0001 | 816 (12.96) | 745 (11.83) | 3.42 |
35–49 years | 13,150 (16.21) | 1705 (27.07) | 1726 (27.41) | 1705 (27.08) | 0.75 | |
50–64 years | 28,704 (35.39) | 2405 (38.19) | 2301 (36.55) | 2405 (38.2) | 3.41 | |
65–79 years | 28,574 (35.23) | 1157 (18.37) | 1213 (19.27) | 1157 (18.38) | 2.28 | |
≥ 80 years | 7607 (9.38) | 284 (4.51) | 240 (3.81) | 284 (4.51) | 3.50 | |
Sex, no. of male (%) | 41,310 (50.93) | 3006 (47.73) | < 0.0001 | 3020 (47.97) | 3006 (47.74) | 0.45 |
Index year | < 0.0001 | |||||
1998–2001 | 18,400 (22.68) | 125 (1.98) | 155 (2.46) | 125 (1.99) | 3.23 | |
2002–2005 | 18,781 (23.15) | 368 (5.84) | 392 (6.23) | 368 (5.84) | 1.60 | |
2006–2009 | 21,093 (26.00) | 2691 (42.73) | 2750 (43.68) | 2691 (42.74) | 1.89 | |
2010–2013 | 22,842 (28.16) | 3114 (49.44) | 2999 (47.63) | 3112 (49.43) | 3.59 | |
Duration of follow-up, years | 3.96 (3.63) | 2.99 (2.32) | < 0.0001 | 3.41 (2.67) | 2.99 (2.32) | 16.88 |
Comorbidities, no. (%) | ||||||
Diabetes mellitus | 46,571 (57.41) | 2496 (39.63) | < 0.0001 | 2453 (38.96) | 2496 (39.64) | 1.40 |
Hypertension | 66,960 (82.55) | 5072 (80.53) | < 0.0001 | 5054 (80.27) | 5070 (80.53) | 0.64 |
Coronary artery disease | 27,645 (34.08) | 1463 (23.23) | < 0.0001 | 1406 (22.33) | 1463 (23.24) | 2.16 |
Peripheral vascular disease | 6647 (8.19) | 359 (5.7) | < 0.0001 | 311 (4.94) | 359 (5.70) | 3.40 |
Heart failure | 25,895 (31.92) | 1276 (20.26) | < 0.0001 | 1265 (20.09) | 1276 (20.27) | 0.44 |
Stroke | 12,349 (15.22) | 539 (8.56) | < 0.0001 | 528 (8.39) | 539 (8.56) | 0.63 |
Chronic obstructive pulmonary disease | 13,984 (17.24) | 690 (10.96) | < 0.0001 | 615 (9.77) | 690 (10.96) | 3.91 |
Hyperlipidemia | 30,513 (37.62) | 2626 (41.7) | < 0.0001 | 2548 (40.47) | 2624 (41.68) | 2.45 |
Rheumatological diseases | 2855 (3.52) | 331 (5.26) | < 0.0001 | 301 (4.78) | 331 (5.26) | 2.18 |
Baseline medication, no. (%) | ||||||
Aspirin | 25,507 (31.45) | 1279 (20.31) | < 0.0001 | 1286 (20.43) | 1279 (20.31) | 0.28 |
Antiplatelet agent | 11,194 (13.8) | 678 (10.77) | < 0.0001 | 659 (10.47) | 678 (10.77) | 0.98 |
Non-steroid anti-inflammation drug | 47,513 (58.57) | 3073 (48.79) | < 0.0001 | 3063 (48.65) | 3071 (48.78) | 0.25 |
Cox-2 selective inhibitors | 4248 (5.24) | 237 (3.76) | < 0.0001 | 217 (3.45) | 237 (3.76) | 1.70 |
Corticosteroids | 19,327 (23.83) | 1595 (25.33) | 0.0072 | 1514 (24.05) | 1593 (25.3) | 2.91 |
Selective serotonin reuptake inhibitors | 2409 (2.97) | 143 (2.27) | 0.0015 | 125 (1.99) | 143 (2.27) | 1.98 |
Anticoagulants | 1807 (2.23) | 94 (1.49) | 0.0001 | 97 (1.54) | 94 (1.49) | 0.39 |
Gastroprotective agents | 27,472 (33.87) | 1981 (31.45) | < 0.0001 | 1908 (30.3) | 1981 (31.46) | 2.51 |
Aldosterone antagonists | 9,199 (11.34) | 461 (7.32) | < 0.0001 | 446 (7.08) | 461 (7.32) | 0.92 |
Calcium channel blocker | 65,926 (81.27) | 5182 (82.28) | 0.0483 | 5160 (81.96) | 5180 (82.27) | 0.83 |
Nitrates | 29,311 (36.13) | 1396 (22.17) | < 0.0001 | 1381 (21.93) | 1396 (22.17) | 0.57 |
HD Hemodialysis; PD Peritoneal dialysis; di, Standardized differences; SD: Standard deviation.