Table 3.
The event numbers and the estimated subdistribution hazard ratios for different types of GI bleeding using a multivariable regression model.
| Before matching | After matching | |||||
|---|---|---|---|---|---|---|
| HD (n = 81,116) | PD (n = 6298) | aSHR (95% CI) | HD (n = 6296) | PD (n = 6296) | aSHR (95% CI) | |
| Overall bleeding, no. (%) | 20,970 (25.85) | 815 (12.94) | 1.23** (1.15–1.33) | 950 (15.09) | 815 (12.94) | 1.13* (1.03–1.24) |
| Upper GI bleeding | 14,150 (17.44) | 567 (9.00) | 1.23** (1.12–1.34) | 653 (10.37) | 567 (9.01) | 1.11 (0.99–1.25) |
| Lower GI bleeding | 1231 (1.52) | 40 (0.64) | 1.49* (1.08–2.06) | 51 (0.81) | 40 (0.64) | 1.26 (0.83–1.91) |
| Unspecified bleeding | 5589 (6.89) | 208 (3.30) | 1.24* (1.09–1.42) | 246 (3.90) | 208 (3.30) | 1.18 (0.99–1.40) |
aSHR Adjusted subdistribution hazard ratio; CI Confidence interval.
aHRs were adjusted for age, sex, selected comorbidities (diabetes mellitus, hypertension, coronary artery disease, peripheral vascular disease, heart failure, stroke, chronic obstructive pulmonary disease, hyperlipidemia, rheumatological disease) and medications (Aspirin, Antiplatelet agent, NSAID, Cox-2 selective inhibitors, Corticosteroids, Selective Serotonin Reuptake Inhibitors, Anticoagulants, Gastroprotective agents, Aldosterone antagonists, Calcium channel blocker, Nitrates).
*p value < 0.05.
**p value < 0.001.