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. 2023 Jan 2;12(1):1. doi: 10.1038/s41389-022-00446-y

Fig. 6. The combination of abiraterone and AKT inhibitor MK2206 synergistically inhibited the growth of PCa xenografts in vivo.

Fig. 6

CWR22Rv1 xenografts were established in the immune-deficient nude mice, and then treated with abiraterone or MK2206A alone or in combination for 15 days. A The growth curves of CWR22Rv1 xenografts. B The body weight of mice during drug treatment. C Tumor nodes were dissected and photoed at the endpoint of animal experiments. D The weight of tumor nodes at the endpoint of animal experiments. Data was represented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.