Table 2.

Multivariate adjusted odds ratios for the association between blood cell ratios and cerebral aneurysm rupture.

	Model 1*	P	Model 2†	P	Model 3‡	P	Model 4§	P
	OR (95% CIs)		OR (95% CIs)		OR (95% CIs)		OR (95% CIs)
PNR
<43.95	Ref		Ref		Ref		Ref
≥43.95	0.439 (0.272–0.709)	0.001	0.440 (0.264–0.734)	0.002	0.426 (0.250–0.727)	0.002	0.356 (0.190–0.668)	0.001
NLR
<2.28	Ref		Ref		Ref		Ref
≥2.28	1.276 (0.786–2.070)	0.324	1.334 (0.803–2.216)	0.266	1.373 (0.813–2.319)	0.236	1.333 (0.731–2.428)	0.348
PLR
<107.56	Ref		Ref		Ref		Ref
≥107.56	0.847 (0.544–1.319)	0.464	0.748 (0.471–1.188)	0.219	0.717 (0.445–1.156)	0.172	0.627 (0.370–1.063)	0.083
PWR
<31.10	Ref		Ref		Ref		Ref
≥31.10	0.190 (0.113–0.319)	<0.001	0.181 (0.105–0.311)	<0.001	0.182 (0.104–0.319)	<0.001	0.250 (0.135–0.464)	<0.001

^*Model 1: no adjustment.

^†Model 2: adjusted for age and sex.

^‡Model 3: adjusted for age, sex, hypertension, diabetes mellitus, hypercholesterolemia, current smoking status, alcohol, cardiovascular disease, family history of subarachnoid hemorrhage, and estimated glomerular filtration rate.

^§Model 4: adjusted for age, sex, hypertension, diabetes mellitus, hypercholesterolemia, current smoking status, alcohol, cardiovascular disease, family history of subarachnoid hemorrhage, estimated glomerular filtration rate, multiplicity, daughter sac, aneurysm size, and aneurysm location.

OR, odds ratio; CIs, confidence intervals; PNR, platelet-to-neutrophil ratio; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; PWR, platelet-to-white blood cell ratio; Ref, reference group.