Fig. 4.

SE-ADM image of normal melanocytes after 5 days of culture. A) A low magnification (1500 ×) SE-AMD image of melanosomes in normal melanocytes with a 7 kV EB. B−D) A high magnification image (10,000 ×) of melanosomes in normal melanocytes. E) Enlarged melanosome images in the normal melanocytes indicated by red arrows in (D). F) Pseudo-coloured melanosomes of (E). G) Pseudo-coloured projection images of the 3D model predicted from melanosome images from (F). H) The prediction 3D model images of melanosomes of (F). The angle of each melanosome is indicated. Scale bars, 10 µm in (A), 1 µm in (B−D) and 200 nm in (E).